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The company

Twist Bioscience Corporation

TWST · Nasdaq

Health CareGenomics & Gene EditingLeadingSynthetic Biology / TechBio

TWST stood above a rising 150-day average in 42 of the last 52 weekly readings, including each of the last 42 weeks. It is 46.4% above that average now. Genomics & Gene Editing: 20% of its 5 stocks in an uptrend (−40 points in four weeks); Health Care: 28% (−9 points in four weeks).

Statistics

Rotation
Leading
Weeks in an uptrend
42 in a row
Industry in uptrend
20% -40 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$274.7M
Officials’ trades on record
3
Institutions holding
315 (+51)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 42 of 52 weeks.

21 Apr – 20 Oct
22%50%78%Apr 26Jun 26Jul 26Sep 26Oct 26

Genomics & Gene Editing: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$112.0M$0Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

3 disclosed lines: House 2, Senate 0, executive 1; 2 people.

WhoDidAmountTraded
Arjun Mody Executive branch: Office of Government EthicsSocial Security Administrationsold$1k–$15k30 Jan 2026filed 10 Apr 2026
Dwight Evans House: U.S. House ClerkPA03sold$1k–$15k30 Mar 2022filed 25 Apr 2022
Dwight Evans House: U.S. House ClerkPA03bought$1k–$15k2 Mar 2020filed 23 Apr 2020

Insiders

Buy orders, 12 months0
Sale orders, 12 months138
Buyers · sellers0 · 10
WhoDidSharesTraded
Adam LaponisChief Financial Officersold2,462at $156.309 Oct 2026filed 13 Oct 2026
Emily M. LeproustChief Executive Officersold1,840at $200.445 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold481at $201.265 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold1,017at $202.325 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold432at $203.615 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold290at $204.805 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold297at $205.785 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold146at $206.845 Oct 2026filed 7 Oct 2026
Emily M. LeproustChief Executive Officersold45at $207.465 Oct 2026filed 7 Oct 2026
Dennis ChoOfficersold9,514at $188.882 Oct 2026filed 5 Oct 2026
Patrick John FinnPresident and COOsold25,714at $188.882 Oct 2026filed 5 Oct 2026
Paula GreenSVP of Human Resourcessold10,088at $188.882 Oct 2026filed 5 Oct 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders315+51 on the quarter
New · exited85 · 33
Reported value$7.3B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
BlackRock, Inc.added · filed 7 Aug 20265,833,891$600.2M+279,529+5.0%
Artisan Partners Limited Partnershipreduced · filed 13 Aug 20264,802,017$494.0M-1,565,760−24.6%
FMR LLCadded · filed 13 Aug 20264,703,044$483.8M+2,813,099+148.8%
ARK Investment Management LLCreduced · filed 14 Aug 20264,549,803$468.1M-1,792,930−28.3%
STATE STREET CORPreduced · filed 7 Aug 20263,232,532$332.6M-438,150−11.9%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 20262,824,989$290.6M+175,888+6.6%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 20262,699,280$277.7M+60,236+2.3%
EdgePoint Investment Group Inc.reduced · filed 14 Aug 20262,521,635$259.4M-2,860,886−53.2%
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLCreduced · filed 12 Aug 20262,174,594$223.7M-3,095,124−58.7%
FARALLON CAPITAL MANAGEMENT, L.L.C.added · filed 14 Aug 20262,136,400$219.8M+708,750+49.6%
31 Mar 2023 – 30 Jun 2026
167238309Mar 23Dec 23Dec 24Sep 25Jun 26

Everyone who traded it

Adam Laponis Company insiderChief Financial Officer · last 9 Oct 20260 · 29
Emily M. Leproust Company insiderChief Executive Officer · last 5 Oct 20260 · 110
Dennis Cho Company insiderOfficer · last 2 Oct 20261 · 65
Patrick John Finn Company insiderPresident and COO · last 2 Oct 20260 · 79
Paula Green Company insiderSVP of Human Resources · last 2 Oct 20260 · 64
Robert F. Werner Company insiderChief Accounting Officer · last 2 Oct 20260 · 44
Katryn Blake Company insiderDirector · last 12 Aug 20260 · 1
Robert Chess Company insiderDirector · last 7 Aug 20260 · 16
Melissa A. Starovasnik Company insiderDirector · last 28 May 20260 · 5
Jan Johannessen Company insiderDirector · last 12 May 20260 · 9
Keith Crandell Company insiderDirector · last 5 Feb 20261 · 2
Nelson Chan Company insiderDirector · last 5 Feb 20260 · 0

Same industry

NTLA Intellia TherapeuticsNot moving yet-10%
EDIT Editas MedicineNot moving yet-10%
BEAM Beam TherapeuticsNot moving yet-12%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Profit per saleFY 2025 · to 30 Sep 202550.7%
Operating profit marginFY 2025 · to 30 Sep 2025-36.2%
Free cash flow marginFY 2025 · to 30 Sep 2025-20.1%
Return on capital employedFY 2025 · to 30 Sep 2025-24.8%
Research spendFY 2025 · to 30 Sep 202521.3%
Share count trendFY 2025 · to 13 Nov 20250.9%
Cash and equivalentsFY 2025 · to 30 Sep 2025$183.0M
Free cash flowFY 2025 · to 30 Sep 2025−$75.6M

Analyst forecasts

No analyst forecasts yet.