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Who

James M. Frates

Chief Financial Officer

Company insider

Files Form 4 as: Chief Financial Officer, Amylyx Pharmaceuticals; Director, Sage Therapeutics; SVP, Alks Inc; CFO ALKS, Alkermes; SVP, CFO & Treasurer, Alkermes.

In numbers

Trades disclosed
811
Buys
3
Sells
110
Bought
$291K
Sold
$45.5M
Companies
4
Companies where not an officer
1
First trade
2 May 2006
Last trade
10 Sep 2026
Last filed
14 Sep 2026

Companies traded

Where they are an officer
AMLX Amylyx PharmaceuticalsOfficer · Biotechnology · last 10 Sep 20261 buy · 12 sells
ALKS AlkermesOfficer · Pharmaceuticals · last 14 May 20200 buys · 74 sells
AlkermesOfficer · last 16 Sep 20110 buys · 20 sells
Everywhere else they filed: board seats, 10% stakes, other companies
Sage TherapeuticsDirector · last 31 Jul 20252 buys · 4 sells

Activity over time

1 Nov 2024 – 1 Oct 2026
10Nov 24May 25Nov 25Apr 26Oct 26

Buys above the line, sells below, each month.

Every trade

TradedCompanyWhatAmount
10 Sep 2026filed 14 Sep 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$315K9,768 at $32.27filing
10 Sep 2026filed 14 Sep 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$35K1,042 at $33.23filing
10 Sep 2026filed 14 Sep 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$315K9,768 at $32.27filing
10 Sep 2026filed 14 Sep 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$35K1,042 at $33.23filing
18 Aug 2026filed 20 Aug 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Code A—22,807 at $0.00filing
18 Aug 2026filed 20 Aug 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Code A—22,807 at $0.00filing
5 Mar 2026filed 9 Mar 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Code A—95,990 at $0.00filing
5 Mar 2026filed 9 Mar 2026AMLX Amylyx Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—143,985 at $0.00filing
5 Mar 2026filed 9 Mar 2026AMLX Amylyx Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—143,985 at $0.00filing
5 Mar 2026filed 9 Mar 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Code A—95,990 at $0.00filing
2 Mar 2026filed 4 Mar 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$115K7,909 at $14.52filing
2 Mar 2026filed 4 Mar 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$115K7,909 at $14.52filing
2 Feb 2026filed 4 Feb 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$52K3,557 at $14.65filing
2 Feb 2026filed 4 Feb 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$52K3,557 at $14.65filing
6 Jan 2026filed 8 Jan 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$37K3,326 at $11.11filing
6 Jan 2026filed 8 Jan 2026AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$37K3,326 at $11.11filing
30 Sep 2025filed 2 Oct 2025AMLX Amylyx PharmaceuticalsBiotechnologySEC FORM 4 Sold$155K10,558 at $14.65filing
31 Jul 2025filed 31 Jul 2025Sage Therapeuticsoption or derivativeSEC FORM 4 Code D—19,154filing
31 Jul 2025filed 31 Jul 2025Sage Therapeuticsoption or derivativeSEC FORM 4 Code D—21,500filing
31 Jul 2025filed 31 Jul 2025Sage TherapeuticsSEC FORM 4 Code U—2,845filing

The newest 500 lines are listed; the numbers count every line.

News

Amylyx Pharmaceuticals (NASDAQ:AMLX) Price Target Raised to $39.00AMLX · dailypolitical.com · 18 Oct 2026Insider Selling: Amylyx Pharmaceuticals (NASDAQ:AMLX) Director Sells 30,000 Shares of StockAMLX · dailypolitical.com · 7 Oct 2026

0 headlines in the last 90 days name James M. Frates; 2 articles from the last 14 days about the 1 company they traded most, at most three about any one of them.

Sectors

Health Care87
Not placed26

Buys in green, sells in red, by the company’s sector.

Related people

Anne Clem WhitakerDirector · Director at Alkermes plc, filing Form 4 there in the last year
Joshua ReedSVP, Chief Financial Officer · SVP, Chief Financial Officer at Alkermes plc, filing Form 4 there in the last year
George M. Milne Jr.Director · Director at Amylyx Pharmaceuticals, filing Form 4 there in the last year
David Joseph GaffinEVP, CLO, Alkermes, Inc. · EVP, CLO, Alkermes, Inc. at Alkermes plc, filing Form 4 there in the last year
Joshua B. CohenCo-Chief Executive Officer · Co-Chief Executive Officer at Amylyx Pharmaceuticals, filing Form 4 there in the last year
Gilbert Ray Cisneros, Jr.Representative, CA-31 · Also traded ALKS in the last 90 days
Camille L. BedrosianChief Medical Officer · Also traded AMLX in the last 90 days
Gina MazzarielloChief Legal Officer · Also traded AMLX in the last 90 days