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Who

Melvin K. Spigelman

Director

Company insider

Files Form 4 as: Director, AN2 Therapeutics; Director, Synergy Pharmaceuticals; Director, Medicines Co /de.

In numbers

Trades disclosed
68
Buys
0
Sells
3
Bought
$0
Sold
$1.6M
Companies
3
Companies where not an officer
3
First trade
25 May 2006
Last trade
19 Mar 2026
Last filed
23 Mar 2026

Companies traded

Everywhere else they filed: board seats, 10% stakes, other companies
ANTX AN2 TherapeuticsDirector · Biotechnology · last 19 Mar 20260 buys · 0 sells
Synergy PharmaceuticalsDirector · last 15 Aug 20180 buys · 0 sells
Medicines Co /deDirector · last 25 May 20180 buys · 3 sells

Activity over time

1 Nov 2024 – 1 Oct 2026
101Nov 24May 25Nov 25Apr 26Oct 26

Buys above the line, sells below, each month.

Every trade

TradedCompanyWhatAmount
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—16,941filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—16,941filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—10,362filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—16,941filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—16,941filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—10,362filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—10,362filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—23,742filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—23,742filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—10,362filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—23,742filing
19 Mar 2026filed 23 Mar 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code D—23,742filing
20 Feb 2026filed 23 Feb 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—20,400 at $0.00filing
20 Feb 2026filed 23 Feb 2026ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—20,400 at $0.00filing
22 May 2025filed 23 May 2025ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—19,111 at $0.00filing
19 Jun 2024filed 21 Jun 2024ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—64,503 at $0.00filing
7 Jun 2023filed 9 Jun 2023ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—23,742 at $0.00filing
12 May 2022filed 16 May 2022ANTX AN2 Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—10,362 at $0.00filing
15 Aug 2018filed 16 Aug 2018Synergy Pharmaceuticalsoption or derivativeSEC FORM 4 Code M—150,000 at $0.00filing
15 Aug 2018filed 16 Aug 2018Synergy PharmaceuticalsSEC FORM 4 Code M$180K150,000 at $1.20filing

News

No headline names them, or the companies they trade most, lately.

Sectors

Not placed3

Buys in green, sells in red, by the company’s sector.

Related people

Kabeer AzizDirector · Director at AN2 Therapeutics, filing Form 4 there in the last year
Gilbert Lynn MarksDirector · Director at AN2 Therapeutics, filing Form 4 there in the last year
Patricia A. MartinDirector · Director at AN2 Therapeutics, filing Form 4 there in the last year
Cameron C. Trenor IIIChief Medical Officer · Chief Medical Officer at AN2 Therapeutics, filing Form 4 there in the last year
Robin Shane ReadnourDirector · Director at AN2 Therapeutics, filing Form 4 there in the last year