Patrick R. O'Neil

Insider · EVP CLO & General Counsel · IONS

Patrick R. O'Neil files insider transactions with the SEC as an evp clo & general counsel of Ionis Pharmaceuticals (IONS). We hold 4 disclosed purchases and sales filed since 3 January 2013, 1 of them in the last 90 days.

Files forIONS
Disclosed buys and sells4 in all, 1 in the last 90 days
Last disclosure2 September 2026

Positions held

2 posts we hold — a term names its own dates; a run of filings only says when they filed

Filed 1 January 2016 — 31 August 2026EVP CLO & General Counsel · Ionis Pharmaceuticals (IONS)299 Form 4 lines · source: SEC Form 4
Filed 1 January 2013 — 1 December 2015SVP, Legal & General Counsel · Isis Pharmaceuticals (ISIS)223 Form 4 lines · source: SEC Form 4

Everything they disclosed

120 entries, newest first — one per disclosure report, one per Form 4 line

was granted 24,205 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2020Restricted Stock Units · traded 15 January 2020 · filed 17 January 2020
exercised options over 12,045 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2020Restricted Stock Units · traded 15 January 2020 · filed 17 January 2020
exercised options over 12,045 shares of Ionis PharmaceuticalsSEC Form 417 January 2020Common Stock · traded 15 January 2020 · filed 17 January 2020
had shares withheld for tax on 4,277 shares of Ionis PharmaceuticalsSEC Form 417 January 2020Common Stock · traded 15 January 2020 · filed 17 January 2020
was granted 54,461 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 January 2020Employee Stock Option (Right to Buy) · traded 2 January 2020 · filed 3 January 2020
acquired or disposed of, other 161 shares of Ionis PharmaceuticalsSEC Form 42 July 2019Common Stock · traded 1 July 2019 · filed 2 July 2019
exercised options over 7,654 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 3 April 2019 · filed 5 April 2019
exercised options over 20,365 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 4 April 2019 · filed 5 April 2019
exercised options over 2,657 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 4 April 2019 · filed 5 April 2019
exercised options over 5,600 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 4 April 2019 · filed 5 April 2019
exercised options over 8,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 4 April 2019 · filed 5 April 2019
exercised options over 2,252 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 April 2019Employee Stock Option (right to buy) · traded 5 April 2019 · filed 5 April 2019
exercised options over 7,654 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 3 April 2019 · filed 5 April 2019
▼ sold on the open market 7,654 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 3 April 2019 · filed 5 April 2019
exercised options over 15,492 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 15,492 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 4,873 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 4,873 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 2,657 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 2,657 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 2,000 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 2,000 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 3,600 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 3,600 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 8,000 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 8,000 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 1,122 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
▼ sold on the open market 1,878 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 4 April 2019 · filed 5 April 2019
exercised options over 2,252 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 5 April 2019 · filed 5 April 2019
▼ sold on the open market 2,252 shares of Ionis PharmaceuticalsSEC Form 45 April 2019Common Stock · traded 5 April 2019 · filed 5 April 2019
exercised options over 28,800 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 420 March 2019Employee Stock Option (right to buy) · traded 18 March 2019 · filed 20 March 2019
exercised options over 28,800 shares of Ionis PharmaceuticalsSEC Form 420 March 2019Common Stock · traded 18 March 2019 · filed 20 March 2019
▼ sold on the open market 28,800 shares of Ionis PharmaceuticalsSEC Form 420 March 2019Common Stock · traded 18 March 2019 · filed 20 March 2019
exercised options over 18,800 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 41 March 2019Employee Stock Option (right to buy) · traded 27 February 2019 · filed 1 March 2019
exercised options over 8,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 41 March 2019Employee Stock Option (right to buy) · traded 27 February 2019 · filed 1 March 2019
exercised options over 4,700 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
▼ sold on the open market 4,700 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
exercised options over 14,100 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
▼ sold on the open market 14,100 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
exercised options over 8,000 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
▼ sold on the open market 8,000 shares of Ionis PharmaceuticalsSEC Form 41 March 2019Common Stock · traded 27 February 2019 · filed 1 March 2019
exercised options over 275 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 414 February 2019Employee Stock Option (right to buy) · traded 12 February 2019 · filed 14 February 2019
exercised options over 275 shares of Ionis PharmaceuticalsSEC Form 414 February 2019Common Stock · traded 12 February 2019 · filed 14 February 2019
▼ sold on the open market 275 shares of Ionis PharmaceuticalsSEC Form 414 February 2019Common Stock · traded 12 February 2019 · filed 14 February 2019
exercised options over 4,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 February 2019Employee Stock Option (right to buy) · traded 1 February 2019 · filed 5 February 2019
exercised options over 15,600 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 45 February 2019Employee Stock Option (right to buy) · traded 5 February 2019 · filed 5 February 2019
exercised options over 4,000 shares of Ionis PharmaceuticalsSEC Form 45 February 2019Common Stock · traded 1 February 2019 · filed 5 February 2019
▼ sold on the open market 4,000 shares of Ionis PharmaceuticalsSEC Form 45 February 2019Common Stock · traded 1 February 2019 · filed 5 February 2019
exercised options over 15,600 shares of Ionis PharmaceuticalsSEC Form 45 February 2019Common Stock · traded 5 February 2019 · filed 5 February 2019
▼ sold on the open market 15,600 shares of Ionis PharmaceuticalsSEC Form 45 February 2019Common Stock · traded 5 February 2019 · filed 5 February 2019
was granted 22,131 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2019Restricted Stock Units · traded 15 January 2019 · filed 17 January 2019
exercised options over 7,823 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2019Restricted Stock Units · traded 15 January 2019 · filed 17 January 2019
exercised options over 7,823 shares of Ionis PharmaceuticalsSEC Form 417 January 2019Common Stock · traded 15 January 2019 · filed 17 January 2019
had shares withheld for tax on 2,734 shares of Ionis PharmaceuticalsSEC Form 417 January 2019Common Stock · traded 15 January 2019 · filed 17 January 2019
was granted 49,800 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 January 2019Employee Stock Option (right to buy) · traded 2 January 2019 · filed 3 January 2019
exercised options over 400 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 January 2019Empoyee Stock Option (right to buy) · traded 3 January 2019 · filed 3 January 2019
exercised options over 4,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 January 2019Employee Stock Option (right to buy) · traded 3 January 2019 · filed 3 January 2019
acquired or disposed of, other 66 shares of Ionis PharmaceuticalsSEC Form 43 January 2019Common Stock · traded 1 January 2019 · filed 3 January 2019
exercised options over 400 shares of Ionis PharmaceuticalsSEC Form 43 January 2019Common Stock · traded 3 January 2019 · filed 3 January 2019
▼ sold on the open market 400 shares of Ionis PharmaceuticalsSEC Form 43 January 2019Common Stock · traded 3 January 2019 · filed 3 January 2019
exercised options over 4,000 shares of Ionis PharmaceuticalsSEC Form 43 January 2019Common Stock · traded 3 January 2019 · filed 3 January 2019
▼ sold on the open market 4,000 shares of Ionis PharmaceuticalsSEC Form 43 January 2019Common Stock · traded 3 January 2019 · filed 3 January 2019
acquired or disposed of, other 66 shares of Ionis PharmaceuticalsSEC Form 43 July 2018Common Stock · traded 1 July 2018 · filed 3 July 2018
exercised options over 1,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 413 March 2018Employee Stock Option (right to buy) · traded 12 March 2018 · filed 13 March 2018
exercised options over 1,000 shares of Ionis PharmaceuticalsSEC Form 413 March 2018Common Stock · traded 12 March 2018 · filed 13 March 2018
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 413 March 2018Common Stock · traded 12 March 2018 · filed 13 March 2018
exercised options over 55 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 431 January 2018Employee Stock Option (right to buy) · traded 29 January 2018 · filed 31 January 2018
exercised options over 300 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 431 January 2018Employee Stock Option (right to buy) · traded 29 January 2018 · filed 31 January 2018
exercised options over 55 shares of Ionis PharmaceuticalsSEC Form 431 January 2018Common Stock · traded 29 January 2018 · filed 31 January 2018
▼ sold on the open market 55 shares of Ionis PharmaceuticalsSEC Form 431 January 2018Common Stock · traded 29 January 2018 · filed 31 January 2018
exercised options over 300 shares of Ionis PharmaceuticalsSEC Form 431 January 2018Common Stock · traded 29 January 2018 · filed 31 January 2018
▼ sold on the open market 300 shares of Ionis PharmaceuticalsSEC Form 431 January 2018Common Stock · traded 29 January 2018 · filed 31 January 2018
exercised options over 645 shares of Ionis PharmaceuticalsSEC Form 429 January 2018Common Stock · traded 25 January 2018 · filed 29 January 2018
▼ sold on the open market 645 shares of Ionis PharmaceuticalsSEC Form 429 January 2018Common Stock · traded 25 January 2018 · filed 29 January 2018
exercised options over 645 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 429 January 2018Employee Stock Option (right to buy) · traded 25 January 2018 · filed 29 January 2018
exercised options over 6,663 shares of Ionis PharmaceuticalsSEC Form 417 January 2018Common Stock · traded 15 January 2018 · filed 17 January 2018
▼ sold on the open market 2,697 shares of Ionis PharmaceuticalsSEC Form 417 January 2018Common Stock · traded 16 January 2018 · filed 17 January 2018
was granted 12,141 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2018Restricted Stock Units · traded 15 January 2018 · filed 17 January 2018
exercised options over 6,663 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 417 January 2018Restricted Stock Units · traded 15 January 2018 · filed 17 January 2018
acquired or disposed of, other 53 shares of Ionis PharmaceuticalsSEC Form 42 January 2018Common Stock · traded 1 January 2018 · filed 2 January 2018
was granted 54,638 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 42 January 2018Employee Stock Option (right to buy) · traded 2 January 2018 · filed 2 January 2018
exercised options over 1,000 shares of Ionis PharmaceuticalsSEC Form 41 December 2017Common Stock · traded 1 December 2017 · filed 1 December 2017
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 41 December 2017Common Stock · traded 1 December 2017 · filed 1 December 2017
exercised options over 1,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 41 December 2017Employee Stock Option (right to buy) · traded 1 December 2017 · filed 1 December 2017
exercised options over 1,000 shares of Ionis PharmaceuticalsSEC Form 43 November 2017Common Stock · traded 1 November 2017 · filed 3 November 2017
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 43 November 2017Common Stock · traded 1 November 2017 · filed 3 November 2017
exercised options over 1,000 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 November 2017Employee Stock Option (right to buy) · traded 1 November 2017 · filed 3 November 2017
exercised options over 200 shares of Ionis PharmaceuticalsSEC Form 46 October 2017Common Stock · traded 5 October 2017 · filed 6 October 2017
▼ sold on the open market 200 shares of Ionis PharmaceuticalsSEC Form 46 October 2017Common Stock · traded 5 October 2017 · filed 6 October 2017
exercised options over 800 shares of Ionis PharmaceuticalsSEC Form 46 October 2017Common Stock · traded 5 October 2017 · filed 6 October 2017
▼ sold on the open market 800 shares of Ionis PharmaceuticalsSEC Form 46 October 2017Common Stock · traded 5 October 2017 · filed 6 October 2017
exercised options over 200 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 46 October 2017Employee Stock Option (right to buy) · traded 5 October 2017 · filed 6 October 2017
exercised options over 800 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 46 October 2017Employee Stock Option (right to buy) · traded 5 October 2017 · filed 6 October 2017
acquired or disposed of, other 134 shares of Ionis PharmaceuticalsSEC Form 43 July 2017Common Stock · traded 1 July 2017 · filed 3 July 2017
exercised options over 70 shares of Ionis PharmaceuticalsSEC Form 42 June 2017Common Stock · traded 1 June 2017 · filed 2 June 2017
▼ sold on the open market 70 shares of Ionis PharmaceuticalsSEC Form 42 June 2017Common Stock · traded 1 June 2017 · filed 2 June 2017
exercised options over 70 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 42 June 2017Employee Stock Option (right to buy) · traded 1 June 2017 · filed 2 June 2017
▼ sold on the open market 150 shares of Ionis PharmaceuticalsSEC Form 43 May 2017Common Stock · traded 1 May 2017 · filed 3 May 2017
exercised options over 500 shares of Ionis PharmaceuticalsSEC Form 43 May 2017Common Stock · traded 1 May 2017 · filed 3 May 2017
▼ sold on the open market 500 shares of Ionis PharmaceuticalsSEC Form 43 May 2017Common Stock · traded 1 May 2017 · filed 3 May 2017
exercised options over 500 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 43 May 2017Employee Stock Option (right to buy) · traded 1 May 2017 · filed 3 May 2017
exercised options over 74 shares of Ionis PharmaceuticalsSEC Form 426 April 2017Common Stock · traded 24 April 2017 · filed 26 April 2017
▼ sold on the open market 74 shares of Ionis PharmaceuticalsSEC Form 426 April 2017Common Stock · traded 24 April 2017 · filed 26 April 2017
exercised options over 426 shares of Ionis PharmaceuticalsSEC Form 426 April 2017Common Stock · traded 24 April 2017 · filed 26 April 2017
▼ sold on the open market 426 shares of Ionis PharmaceuticalsSEC Form 426 April 2017Common Stock · traded 24 April 2017 · filed 26 April 2017
exercised options over 74 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 426 April 2017Employee Stock Option (right to buy) · traded 24 April 2017 · filed 26 April 2017
exercised options over 426 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 426 April 2017Employee Stock Option (right to buy) · traded 24 April 2017 · filed 26 April 2017
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 413 April 2017Common Stock · traded 12 April 2017 · filed 13 April 2017
exercised options over 500 shares of Ionis PharmaceuticalsSEC Form 42 March 2017Common Stock · traded 1 March 2017 · filed 2 March 2017
▼ sold on the open market 500 shares of Ionis PharmaceuticalsSEC Form 42 March 2017Common Stock · traded 1 March 2017 · filed 2 March 2017
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 42 March 2017Common Stock · traded 1 March 2017 · filed 2 March 2017
exercised options over 500 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 42 March 2017Employee Stock Option (right to buy) · traded 1 March 2017 · filed 2 March 2017
▼ sold on the open market 1,000 shares of Ionis PharmaceuticalsSEC Form 48 February 2017Common Stock · traded 6 February 2017 · filed 8 February 2017
exercised options over 19 shares of Ionis PharmaceuticalsSEC Form 48 February 2017Common Stock · traded 6 February 2017 · filed 8 February 2017
▼ sold on the open market 19 shares of Ionis PharmaceuticalsSEC Form 48 February 2017Common Stock · traded 6 February 2017 · filed 8 February 2017
exercised options over 481 shares of Ionis PharmaceuticalsSEC Form 48 February 2017Common Stock · traded 6 February 2017 · filed 8 February 2017
▼ sold on the open market 481 shares of Ionis PharmaceuticalsSEC Form 48 February 2017Common Stock · traded 6 February 2017 · filed 8 February 2017
exercised options over 19 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 48 February 2017Employee Stock Option (right to buy) · traded 6 February 2017 · filed 8 February 2017
exercised options over 481 shares of Ionis Pharmaceuticals (a derivative holding)SEC Form 48 February 2017Employee Stock Option (right to buy) · traded 6 February 2017 · filed 8 February 2017
exercised options over 312 shares of Ionis PharmaceuticalsSEC Form 418 January 2017Common Stock · traded 15 January 2017 · filed 18 January 2017

Positions come from the unitedstates/congress-legislators roster, the Office of Government Ethics and the SEC’s Form 4 index. Every disclosed line names its own source and links the document the government published; we print what the filing says and never a price we did not read from it. Headlines and links come from the GDELT Global Knowledge Graph — the story stays with the publisher. The portrait, where we have one, is the public-domain Congressional Bioguide photograph.