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The company

Iovance Biotherapeutics, Inc.

IOVA · Nasdaq

Health CareBiotechnologyLeading

IOVA stood above a rising 150-day average in 42 of the last 52 weekly readings, including each of the last 42 weeks. It is 125.5% above that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Leading
Weeks in an uptrend: 42 in a row
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $0
Officials’ trades on record: 0
Institutions holding: 273 (+7)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 42 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months0

Buyers · sellers0 · 0

No open-market buy or sale by its insiders on record.

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders273+7 on the quarter

New · exited44 · 37

Reported value$1.2B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
BlackRock, Inc.added · filed 7 Aug 2026	36,957,681$153.7M	+5,877,176+18.9%
MHR FUND MANAGEMENT LLCunchanged · filed 14 Aug 2026	28,967,103$120.5M	00.0%
STATE STREET CORPadded · filed 7 Aug 2026	24,478,268$101.8M	+7,030,160+40.3%
TWO SIGMA INVESTMENTS, LPadded · filed 14 Aug 2026	19,010,697$79.1M	+5,323,264+38.9%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	18,204,248$75.7M	+1,586,511+9.5%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 2026	14,388,999$59.9M	+2,688,155+23.0%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 2026	10,324,826$43.0M	+1,752,228+20.4%
MILLENNIUM MANAGEMENT LLCreduced · filed 14 Aug 2026	8,525,919$35.5M	-888,373−9.4%
DIMENSIONAL FUND ADVISORS LPadded · filed 11 Aug 2026	6,460,449$26.9M	+3,814,747+144.2%
Palo Alto Investors LPreduced · filed 17 Aug 2026	5,296,209$22.0M	-1,053,354−16.6%