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The company

Xeris Biopharma Holdings, Inc.

XERS · Nasdaq

Health CareBiotechnologyLeading

XERS stood above a rising 150-day average in 29 of the last 52 weekly readings, including each of the last 15 weeks. It is 37.7% above that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Leading
Weeks in an uptrend: 15 in a row
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $8.9M
Officials’ trades on record: 0
Institutions holding: 226 (+11)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 29 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months32

Buyers · sellers0 · 9

Who	Did	Shares	Traded
Beth HechtOfficer	sold	16,666at $9.41	1 Oct 2026filed 2 Oct 2026
Kevin McCullochOfficer	sold	15,000at $9.41	1 Oct 2026filed 2 Oct 2026
Steven PieperOfficer	sold	5,000at $9.41	1 Oct 2026filed 2 Oct 2026
Kevin McCullochOfficer	sold	25,000at $10.00	28 Sep 2026filed 29 Sep 2026
Beth HechtOfficer	sold	16,666at $8.49	1 Sep 2026filed 1 Sep 2026
Steven PieperOfficer	sold	5,000at $8.50	1 Sep 2026filed 1 Sep 2026
Kevin McCullochOfficer	sold	15,000at $8.49	1 Sep 2026filed 1 Sep 2026
Steven PieperOfficer	sold	5,000at $8.50	12 Aug 2026filed 12 Aug 2026
Beth HechtOfficer	sold	16,666at $8.01	3 Aug 2026filed 4 Aug 2026
Kevin McCullochOfficer	sold	15,000at $8.02	3 Aug 2026filed 4 Aug 2026
Steven PieperOfficer	sold	27,600at $8.52	7 Jul 2026filed 7 Jul 2026
Steven PieperOfficer	sold	17,400at $8.50	6 Jul 2026filed 7 Jul 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders226+11 on the quarter

New · exited41 · 31

Reported value$859.5M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
BlackRock, Inc.added · filed 7 Aug 2026	14,525,539$115.0M	+1,579,754+12.2%
D. E. Shaw & Co., Inc.added · filed 14 Aug 2026	7,804,758$61.8M	+15,947+0.2%
VANGUARD CAPITAL MANAGEMENT LLCnew · filed 13 Aug 2026	7,340,229$58.1M	+7,340,229
STATE STREET CORPadded · filed 7 Aug 2026	4,821,566$38.2M	+163,392+3.5%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 2026	4,718,183$37.4M	+427,554+10.0%
Nuveen, LLCadded · filed 11 Aug 2026	4,385,141$34.7M	+1,468,543+50.4%
Rosalind Advisors, Inc.reduced · filed 14 Aug 2026	2,908,981$23.0M	-322,719−10.0%
Qube Research & Technologies Ltdreduced · filed 14 Aug 2026	2,893,749$22.9M	-1,220,676−29.7%
VANGUARD PORTFOLIO MANAGEMENT LLCnew · filed 13 Aug 2026	2,626,208$20.8M	+2,626,208
WELLINGTON MANAGEMENT GROUP LLPadded · filed 14 Aug 2026	2,365,103$18.7M	+193,749+8.9%