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Who

Phillip Et Al Frost

Director and 10% owner

Company insider

Files Form 4 as: 10% owner, Nocopi Technologies Inc/md/; Director and 10% owner, Cocrystal Pharma; CEO & Chairman, Opko Health; Director and 10% owner, Fluent; 10% owner, BioCardia; Director and 10% owner, Castle Brands; 10% owner, Non Invasive Monitoring Systems Inc /fl/; Director and 10% owner and Other, Ladenburg Thalmann Financial Services.

Every Form 4 they filed

In numbers

Trades disclosed
7,128
Buys
967
Sells
20
Bought
$363.7M
Sold
$137.8M
Companies
21
Companies where not an officer
19
First trade
31 Dec 2005
Last trade
11 Sep 2026
Last filed
14 Sep 2026

Companies traded

Where they are an officer
OPK Opko HealthDirector, Officer, 10% owner · Biotechnology · last 31 Oct 2025802 buys · 0 sells
IvaxDirector, Officer, 10% owner · last 26 Jan 20060 buys · 0 sells
Everywhere else they filed: board seats, 10% stakes, other companies
Nocopi Technologies Inc/md/10% owner · last 11 Sep 20261 buy · 0 sells
COCP Cocrystal PharmaDirector, 10% owner · Biotechnology · last 5 Aug 202612 buys · 0 sells
FLNT FluentDirector, 10% owner · Advertising & Marketing · last 4 Sep 202512 buys · 0 sells
BCDA BioCardia10% owner · Biotechnology · last 19 Jan 202412 buys · 1 sell
Castle BrandsDirector, 10% owner · last 8 Oct 201914 buys · 0 sells
Non Invasive Monitoring Systems Inc /fl/10% owner · last 24 Jan 20191 buy · 0 sells
Ladenburg Thalmann Financial ServicesDirector, 10% owner, Other · last 24 Dec 201851 buys · 1 sell
Vector Group10% owner · last 26 Nov 20182 buys · 3 sells
ELOX Eloxx PharmaceuticalsDirector, 10% owner, Other · Biotechnology · last 19 Dec 20171 buy · 0 sells
NAGE Niagen Bioscience10% owner · Pharmaceuticals · last 30 Dec 20133 buys · 0 sells
SafeStitch MedicalDirector, 10% owner · last 3 Sep 201310 buys · 0 sells
PROLOR BiotechDirector, 10% owner · last 29 Aug 201324 buys · 1 sell

Activity over time

1 Nov 2024 – 1 Oct 2026
04Nov 24May 25Nov 25Apr 26Oct 26

Buys above the line, sells below, each month.

Every trade

TradedCompanyWhatAmount
11 Sep 2026filed 14 Sep 2026Nocopi Technologies Inc/md/SEC FORM 4 Code A—21,930 at $0.00filing
5 Aug 2026filed 6 Aug 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$9,81610,000 at $0.9816filing
5 Aug 2026filed 6 Aug 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$9,80010,000 at $0.98filing
3 Aug 2026filed 5 Aug 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$71K75,000 at $0.9412filing
3 Aug 2026filed 5 Aug 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$71K75,000 at $0.94filing
24 Feb 2026filed 25 Feb 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$20K20,000 at $0.9976filing
24 Feb 2026filed 25 Feb 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$20K20,000 at $1.00filing
6 Feb 2026filed 9 Feb 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$47K50,000 at $0.9456filing
6 Feb 2026filed 9 Feb 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$48K50,000 at $0.95filing
9 Jan 2026filed 13 Jan 2026COCP Cocrystal Pharmaoption or derivative · BiotechnologySEC FORM 4 Code A—24,615 at $0.00filing
9 Jan 2026filed 13 Jan 2026COCP Cocrystal Pharmaoption or derivative · BiotechnologySEC FORM 4 Code A—24,615 at $0.00filing
31 Dec 2025filed 2 Jan 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$47K50,000 at $0.9455filing
31 Dec 2025filed 2 Jan 2026COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$48K50,000 at $0.95filing
30 Dec 2025filed 31 Dec 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$19K20,000 at $0.97filing
26 Dec 2025filed 29 Dec 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$39K40,000 at $0.97filing
24 Dec 2025filed 29 Dec 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$24K25,000 at $0.97filing
26 Nov 2025filed 28 Nov 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$1,5001,500 at $1.00filing
26 Nov 2025filed 28 Nov 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$2,4752,500 at $0.99filing
25 Nov 2025filed 25 Nov 2025COCP Cocrystal PharmaBiotechnologySEC FORM 4 Bought$19K20,000 at $0.94filing
31 Oct 2025filed 31 Oct 2025OPK Opko HealthBiotechnologySEC FORM 4 Bought$213K150,000 at $1.42filing

The newest 500 lines are listed; the numbers count every line.

Sectors

Health Care844
Communications12
Industrials1
Not placed130

Buys in green, sells in red, by the company’s sector.

Related people

Adam LogalSr. Vice President, CFO · Sr. Vice President, CFO at Opko Health, filing Form 4 there in the last year
Steven D. RubinDirector · Executive VP-Administration at Opko Health, filing Form 4 there in the last year
John A. PaganelliDirector · Director at Opko Health, filing Form 4 there in the last year
Roger MedelDirector · Director at Opko Health, filing Form 4 there in the last year
Richard C. Pfenniger Jr.Director · Director at Opko Health, filing Form 4 there in the last year
Peter AltmanPresident and CEO · Also traded BCDA in the last 90 days
GLOBAL VALUE INVESTMENT CORP.10% owner · Also traded FLNT in the last 90 days
James GeyganDirector and 10% owner · Also traded FLNT in the last 90 days