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The company

Opko Health, Inc.

OPK · Nasdaq

Health CareBiotechnologyJust started moving

OPK stood above a rising 150-day average in 13 of the last 52 weekly readings, including each of the last 10 weeks. It is 19.3% above that average now. Biotechnology: 18% of its 561 stocks in an uptrend (−9 points in four weeks); Health Care: 28% (−6 points in four weeks).

SEC filings

Statistics

Rotation: Just started moving
Weeks in an uptrend: 10 in a row
Industry in uptrend: 18% -9 in 4 wk
Insider buys, 12 months: $3.2M
Insider sales, 12 months: $0
Officials’ trades on record: 3
Institutions holding: 217 (-2)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 13 of 52 weeks.

23 Apr – 22 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has been slipping.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

3 disclosed lines: House 3, Senate 0, executive 0; 2 people.

Who	Did	Amount	Traded
Carlos Curbelo House: U.S. House ClerkFL26	bought	$1k–$15k	26 Sep 2017filed 3 Oct 2017
Carlos Curbelo House: U.S. House ClerkFL26	bought	$1k–$15k	2 Mar 2017filed 2 Mar 2017
Carlos Curbelo House: U.S. House ClerkFL26	bought	$1k–$15k	7 Feb 2017filed 7 Feb 2017

Insiders

Buy orders, 12 months6

Sale orders, 12 months0

Buyers · sellers3 · 0

Who	Did	Shares	Traded
John A. PaganelliDirector	bought	10,000at $1.14	20 Mar 2026filed 20 Mar 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders217-2 on the quarter

New · exited27 · 31

Reported value$307.1M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Rubric Capital Management LPunchanged · filed 14 Aug 2026	47,791,243$71.7M	00.0%
BlackRock, Inc.added · filed 7 Aug 2026	36,978,893$55.5M	+746,670+2.1%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	14,968,930$22.5M	+469,766+3.2%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 2026	14,934,924$22.4M	+165,205+1.1%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 2026	11,581,027$17.4M	+279,526+2.5%
STATE STREET CORPadded · filed 7 Aug 2026	10,309,070$15.5M	+807,693+8.5%
GOLDMAN SACHS GROUP INCreduced · filed 14 Aug 2026	7,035,492$10.6M	-639,534−8.3%
UBS Group AGreduced · filed 13 Aug 2026	5,006,284$7.5M	-1,065,148−17.5%
Whitefort Capital Management, LPadded · filed 14 Aug 2026	4,511,412$6.8M	+258,072+6.1%
NORTHERN TRUST CORPadded · filed 13 Aug 2026	3,756,163$5.6M	+136,817+3.8%