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The company

Alnylam Pharmaceuticals, Inc.

ALNY · Nasdaq

Health CareBiotechnologyNot moving yet

ALNY stood above a rising 150-day average in 7 of the last 52 weekly readings, and has been out of that trend for the last 45 weeks. It is 16.2% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

Statistics

Rotation
Not moving yet
Weeks in an uptrend
out for 45
Industry in uptrend
15% -17 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$70.4M
Officials’ trades on record
28
Institutions holding
745 (-3)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 7 of 52 weeks.

17 Apr – 16 Oct
16%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$26.1M$0Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

28 disclosed lines: House 17, Senate 1, executive 10; 7 people.

WhoDidAmountTraded
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k28 Aug 2026filed 8 Oct 2026
Cory A. Booker Senate: U.S. Senate eFDSenatorsoldspouse$1k–$15k11 Aug 2026filed 9 Sep 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k10 Aug 2026filed 8 Oct 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k17 Jul 2026filed 22 Sep 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officesold$15k–$50k16 Jun 2026filed 22 Aug 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officesold$1k–$15k18 May 2026filed 1 Jul 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k15 Apr 2026filed 1 Jul 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k7 Apr 2026filed 1 Jul 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k23 Mar 2026filed 14 May 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officesold$1k–$15k19 Feb 2026filed 14 May 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officebought$1k–$15k23 Jan 2026filed 14 May 2026
Jefferson Shreve House: U.S. House ClerkIN06sold$15k–$50k12 May 2025filed 22 Jun 2025

Insiders

Buy orders, 12 months0
Sale orders, 12 months34
Buyers · sellers0 · 8
WhoDidSharesTraded
Bryan SupranEVP, CLO and Secretarysold1,758at $226.882 Oct 2026filed 6 Oct 2026
David E. I. PyottDirectorsold921at $297.711 Jun 2026filed 3 Jun 2026
David E. I. PyottDirectorsold1,175at $298.911 Jun 2026filed 3 Jun 2026
David E. I. PyottDirectorsold1,222at $299.871 Jun 2026filed 3 Jun 2026
David E. I. PyottDirectorsold495at $300.721 Jun 2026filed 3 Jun 2026
David E. I. PyottDirectorsold17at $302.651 Jun 2026filed 3 Jun 2026
Melissa McLaughlinChief Human Resources Officersold56at $320.146 Apr 2026filed 7 Apr 2026
Melissa McLaughlinChief Human Resources Officersold909at $329.766 Apr 2026filed 7 Apr 2026
Melissa McLaughlinChief Human Resources Officersold829at $330.466 Apr 2026filed 7 Apr 2026
Melissa McLaughlinChief Human Resources Officersold293at $331.896 Apr 2026filed 7 Apr 2026
Melissa McLaughlinChief Human Resources Officersold199at $333.946 Apr 2026filed 7 Apr 2026
Melissa McLaughlinChief Human Resources Officersold265at $316.612 Apr 2026filed 7 Apr 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders745-3 on the quarter
New · exited87 · 90
Reported value$38.0B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
FMR LLCadded · filed 13 Aug 202615,023,962$4.5B+444,796+3.1%
Capital World Investorsadded · filed 12 Aug 202611,144,846$3.4B+342,498+3.2%
BlackRock, Inc.added · filed 7 Aug 202610,907,675$3.3B+462,767+4.4%
Capital Research Global Investorsadded · filed 12 Aug 20269,750,699$2.9B+279,518+3.0%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 20266,538,390$2.0B+47,110+0.7%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 20266,029,478$1.8B+82,772+1.4%
Invesco Ltd.added · filed 14 Aug 20263,754,318$1.1B+2,462,592+190.6%
STATE STREET CORPadded · filed 7 Aug 20263,555,689$1.1B+232,991+7.0%
JPMORGAN CHASE & COnew · filed 12 Aug 20262,675,517$785.3M+2,675,517
GEODE CAPITAL MANAGEMENT, LLCreduced · filed 12 Aug 20262,635,840$791.3M-24,545−0.9%
31 Mar 2023 – 30 Jun 2026
403593783Mar 23Dec 23Dec 24Sep 25Jun 26

Everyone who traded it

Bryan Supran Company insiderEVP, CLO and Secretary · last 2 Oct 20260 · 1
Yvonne Greenstreet Company insiderChief Executive Officer · last 19 Sep 20260 · 33
Donald J. Trump Executive branchWhite House Office · last 28 Aug 20267 · 3
Cory A. Booker SenateSenator · last 11 Aug 20260 · 1
Benjamin Cravatt Company insiderDirector · last 1 Jun 20260 · 0
David E. I. Pyott Company insiderDirector · last 1 Jun 20261 · 3
Amy W. Schulman Company insiderDirector · last 20 May 20260 · 2
Charles Elliott Sigal Company insiderDirector · last 20 May 20260 · 0
Colleen F. Reitan Company insiderDirector · last 20 May 20262 · 2
Dennis A. Ausiello Company insiderDirector · last 20 May 20260 · 11
Margaret A. Hamburg Company insiderDirector · last 20 May 20260 · 0
Olivier Brandicourt Company insiderDirector · last 20 May 20260 · 0

Same industry

MRNA ModernaLeading+147%
ENTX Entera BioLeading+37%
XNCR XencorLeading+30%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Profit per saleFY 2025 · to 31 Dec 202581.8%
Operating profit marginFY 2025 · to 31 Dec 202513.5%
Free cash flow marginFY 2025 · to 31 Dec 202512.5%
Return on capital employedFY 2025 · to 31 Dec 202514.3%
Cash conversionFY 2025 · to 31 Dec 2025167%
Research spendFY 2025 · to 31 Dec 202535.5%
Earnings per share growthFY 2025 · to 31 Dec 202554.3%
Share count trendFY 2025 · to 6 Feb 20260.2%
Cash and equivalentsFY 2025 · to 31 Dec 2025$1.7B
Free cash flowFY 2025 · to 31 Dec 2025$465.4M

Analyst forecasts

No analyst forecasts yet.