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The company

AnaptysBio, Inc.

ANAB · Nasdaq

Health CareBiotechnologyNot moving yet

ANAB stood above a rising 150-day average in 48 of the last 52 weekly readings, and has been out of that trend for the last 4 weeks. It is 9.8% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 4
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $16.2M
Officials’ trades on record: 0
Institutions holding: 204 (+7)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 48 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months25

Buyers · sellers0 · 8

Who	Did	Shares	Traded
Hollings RentonDirector	sold	5,000at $49.87	1 Oct 2026filed 2 Oct 2026
John P. SchmidDirector	sold	12,596at $55.71	30 Mar 2026filed 1 Apr 2026
John P. SchmidDirector	sold	7,527at $56.70	30 Mar 2026filed 1 Apr 2026
John P. SchmidDirector	sold	522at $57.40	30 Mar 2026filed 1 Apr 2026
Daniel FagaPresident, CEO	sold	510at $56.61	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	2,570at $57.91	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	3,662at $58.62	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	490at $59.62	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	550at $60.63	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	1,012at $62.15	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	2,592at $63.35	27 Mar 2026filed 27 Mar 2026
Daniel FagaPresident, CEO	sold	3,155at $64.19	27 Mar 2026filed 27 Mar 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders204+7 on the quarter

New · exited46 · 38

Reported value$2.0B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
EcoR1 Capital, LLCunchanged · filed 14 Aug 2026	7,880,094$531.9M	00.0%
BlackRock, Inc.added · filed 7 Aug 2026	1,844,049$124.5M	+162,669+9.7%
TANG CAPITAL MANAGEMENT LLCunchanged · filed 14 Aug 2026	1,330,879$89.8M	00.0%
STATE STREET CORPadded · filed 7 Aug 2026	1,286,194$86.8M	+293,749+29.6%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	906,233$61.2M	+53,082+6.2%
Affinity Asset Advisors, LLCreduced · filed 13 Aug 2026	826,109$55.8M	-113,891−12.1%
Sanofiunchanged · filed 28 Jul 2026	821,917$55.5M	00.0%
MILLENNIUM MANAGEMENT LLCadded · filed 14 Aug 2026	807,316$54.5M	+331,744+69.8%
Woodline Partners LPadded · filed 14 Aug 2026	717,014$48.4M	+372,758+108.3%
683 Capital Management, LLCadded · filed 14 Aug 2026	660,000$44.6M	+35,000+5.6%