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The company

Annexon, Inc.

ANNX · Nasdaq

Health CareBiotechnologyNot moving yet

ANNX stood above a rising 150-day average in 37 of the last 52 weekly readings, and has been out of that trend for the last 13 weeks. It is 34.0% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 13
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $16.0M
Insider sales, 12 months: $627K
Officials’ trades on record: 0
Institutions holding: 208 (+2)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 37 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months14

Sale orders, 12 months10

Buyers · sellers4 · 5

Who	Did	Shares	Traded
Douglas LovePRESIDENT AND CEO	bought	26,065at $3.83	24 Sep 2026filed 25 Sep 2026
Muneer A. SatterDirector	bought	613,497at $5.41	28 May 2026filed 29 May 2026
William H. CarsonDirector	bought	8,000at $5.78	11 May 2026filed 13 May 2026
William H. CarsonDirector	bought	8,000at $6.20	10 Apr 2026filed 14 Apr 2026
William H. CarsonDirector	bought	8,000at $5.67	10 Mar 2026filed 12 Mar 2026
Jennifer LewEVP & CHIEF FINANCIAL OFFICER	sold	5,565at $5.42	2 Mar 2026filed 4 Mar 2026
Jamie DananbergCHIEF MEDICAL OFFICER	sold	5,820at $5.43	2 Mar 2026filed 4 Mar 2026
Michael OverdorfEVP & CHIEF BUSINESS OFFICER	sold	4,339at $5.42	2 Mar 2026filed 4 Mar 2026
Ted YednockEVP & CHIEF INNOVATION OFFICER	sold	5,566at $5.42	2 Mar 2026filed 4 Mar 2026
Dean Richard ArtisEVP & CHIEF SCIENTIFIC OFFICER	sold	5,894at $5.43	2 Mar 2026filed 4 Mar 2026
Jennifer LewEVP & CHIEF FINANCIAL OFFICER	sold	7,851at $5.11	18 Feb 2026filed 20 Feb 2026
Jamie DananbergCHIEF MEDICAL OFFICER	sold	5,290at $5.10	18 Feb 2026filed 20 Feb 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders208+2 on the quarter

New · exited31 · 29

Reported value$1.0B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
FMR LLCadded · filed 13 Aug 2026	19,518,496$111.5M	+8,882,848+83.5%
BlackRock, Inc.added · filed 7 Aug 2026	13,539,744$77.3M	+2,601,235+23.8%
Redmile Group, LLCreduced · filed 14 Aug 2026	11,869,877$67.8M	-2,679,891−18.4%
STATE STREET CORPadded · filed 7 Aug 2026	9,824,321$56.1M	+2,905,066+42.0%
BVF INCunchanged · filed 14 Aug 2026	8,698,173$49.7M	00.0%
Woodline Partners LPadded · filed 14 Aug 2026	6,925,067$39.5M	+4,587,930+196.3%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	6,871,015$39.2M	+914,426+15.4%
MAK CAPITAL ONE LLCadded · filed 14 Aug 2026	5,862,180$33.5M	+1,138,137+24.1%
GOLDMAN SACHS GROUP INCadded · filed 14 Aug 2026	5,825,579$33.3M	+3,672,699+170.6%
Siren, L.L.C.added · filed 13 Aug 2026	4,458,646$25.5M	+500,000+12.6%