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The company

Arrowhead Pharmaceuticals, Inc.

ARWR · Nasdaq

Health CareBiotechnologyNot moving yet

ARWR stood above a rising 150-day average in 46 of the last 52 weekly readings, and has been out of that trend for the last 6 weeks. It is 21.0% below that average now. Biotechnology: 18% of its 561 stocks in an uptrend (−14 points in four weeks); Health Care: 28% (−9 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 6
Industry in uptrend: 18% -14 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $47.6M
Officials’ trades on record: 1
Institutions holding: 465 (+64)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 46 of 52 weeks.

21 Apr – 20 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

1 disclosed lines: House 1, Senate 0, executive 0; 1 people.

Who	Did	Amount	Traded
Daniel S. Goldman House: U.S. House ClerkNY10	sold	$1k–$15k	31 Jan 2023filed 24 Feb 2023

Insiders

Buy orders, 12 months0

Sale orders, 12 months21

Buyers · sellers0 · 10

Who	Did	Shares	Traded
Adeoye Y. OlukotunDirector	sold	2,000at $86.96	18 Aug 2026filed 20 Aug 2026
Michael S. PerryDirector	sold	11,600at $87.30	18 Aug 2026filed 20 Aug 2026
Hongbo LuDirector	sold	2,970at $76.88	12 May 2026filed 14 May 2026
James C. HamiltonChief Medical Officer	sold	10,000at $75.00	23 Apr 2026filed 24 Apr 2026
Daniel Joseph ApelChief Financial Officer	sold	3,208at $70.11	22 Apr 2026filed 24 Apr 2026
Daniel Joseph ApelChief Financial Officer	sold	1,157at $70.45	22 Apr 2026filed 24 Apr 2026
Daniel Joseph ApelChief Financial Officer	sold	8,730at $71.92	22 Apr 2026filed 24 Apr 2026
James C. HamiltonChief Medical Officer	sold	10,000at $64.19	5 Mar 2026filed 9 Mar 2026
Patrick O'BrienCOO	sold	4,368at $61.20	5 Jan 2026filed 5 Jan 2026
Patrick O'BrienCOO	sold	6,164at $62.23	5 Jan 2026filed 5 Jan 2026
Patrick O'BrienCOO	sold	13,451at $62.96	5 Jan 2026filed 5 Jan 2026
Patrick O'BrienCOO	sold	11,842at $63.84	5 Jan 2026filed 5 Jan 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders465+64 on the quarter

New · exited123 · 62

Reported value$9.6B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
BlackRock, Inc.reduced · filed 7 Aug 2026	14,830,553$1.2B	-3,330,966−18.3%
Avoro Capital Advisors LLCadded · filed 14 Aug 2026	11,355,555$925.6M	+655,556+6.1%
FMR LLCadded · filed 13 Aug 2026	8,039,804$655.3M	+773,152+10.6%
VANGUARD PORTFOLIO MANAGEMENT LLCreduced · filed 13 Aug 2026	6,351,355$517.7M	-794,781−11.1%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	6,110,953$498.1M	+78,537+1.3%
STATE STREET CORPreduced · filed 7 Aug 2026	5,694,640$464.2M	-801,490−12.3%
NORGES BANKnew · filed 12 Aug 2026	3,896,536$317.6M	+3,896,536
Invesco Ltd.added · filed 14 Aug 2026	3,883,976$316.6M	+603,329+18.4%
GEODE CAPITAL MANAGEMENT, LLCreduced · filed 12 Aug 2026	3,530,612$298.8M	-748,216−17.5%
FRED ALGER MANAGEMENT, LLCreduced · filed 14 Aug 2026	3,301,919$269.1M	-40,574−1.2%