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The company

Bicycle Therapeutics plc - American Depositary Shares

BCYC · Nasdaq

Health CareBiotechnologyNot moving yet

BCYC stood above a rising 150-day average in 0 of the last 52 weekly readings. It is 17.2% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 52
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $981K
Officials’ trades on record: 0
Institutions holding: 99 (+6)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 0 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months44

Buyers · sellers0 · 8

Who	Did	Shares	Traded
Michael SkynnerCHIEF SCIENTIFIC OFFICER	sold	503at $3.57	5 Oct 2026filed 6 Oct 2026
Kevin LeeCHIEF EXECUTIVE OFFICER	sold	1,638at $3.57	5 Oct 2026filed 6 Oct 2026
Travis Alvin ThompsonChief Financial Officer	sold	79at $3.57	5 Oct 2026filed 6 Oct 2026
Michael Charles Ferguson HannayCHIEF PROD & SUPPLY CHAIN OFF	sold	242at $3.57	5 Oct 2026filed 6 Oct 2026
Jennifer Scott PerryChief Operating Officer	sold	80at $3.56	5 Oct 2026filed 6 Oct 2026
Jennifer Scott PerryChief Operating Officer	sold	326at $3.78	5 Oct 2026filed 6 Oct 2026
Jennifer Scott PerryChief Operating Officer	sold	30at $3.57	5 Oct 2026filed 7 Oct 2026
Jennifer Scott PerryChief Operating Officer	sold	326at $3.78	5 Oct 2026filed 7 Oct 2026
Michael SkynnerCHIEF SCIENTIFIC OFFICER	sold	1,942at $3.47	2 Oct 2026filed 6 Oct 2026
Kevin LeeCHIEF EXECUTIVE OFFICER	sold	6,167at $3.47	2 Oct 2026filed 6 Oct 2026
Travis Alvin ThompsonChief Financial Officer	sold	893at $3.47	2 Oct 2026filed 6 Oct 2026
Michael Charles Ferguson HannayCHIEF PROD & SUPPLY CHAIN OFF	sold	1,572at $3.47	2 Oct 2026filed 6 Oct 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders99+6 on the quarter

New · exited20 · 14

Reported value$145.4M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
BAKER BROS. ADVISORS LPunchanged · filed 14 Aug 2026	10,885,357$46.2M	00.0%
FCPM III SERVICES B.V.unchanged · filed 14 Aug 2026	3,468,430$14.7M	00.0%
ARMISTICE CAPITAL, LLCunchanged · filed 14 Aug 2026	3,398,000$14.4M	00.0%
Long Focus Capital Management, LLCunchanged · filed 14 Aug 2026	3,310,687$14.0M	00.0%
RENAISSANCE TECHNOLOGIES LLCadded · filed 13 Aug 2026	1,533,400$6.5M	+554,100+56.6%
GSK plcunchanged · filed 13 Aug 2026	1,529,561$6.5M	00.0%
MARSHALL WACE, LLPadded · filed 13 Aug 2026	797,940$3.4M	+420,605+111.5%
Qube Research & Technologies Ltdadded · filed 14 Aug 2026	775,567$3.3M	+466,950+151.3%
MORGAN STANLEYadded · filed 13 Aug 2026	667,269$2.8M	+46,942+7.6%
SCHRODER INVESTMENT MANAGEMENT GROUPunchanged · filed 13 Aug 2026	615,833$2.6M	00.0%