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The company

C4 Therapeutics, Inc.

CCCC · Nasdaq

Health CareBiotechnologyNot moving yet

CCCC stood above a rising 150-day average in 35 of the last 52 weekly readings, and has been out of that trend for the last 5 weeks. It is 19.7% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 5
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $44K
Officials’ trades on record: 0
Institutions holding: 145 (+27)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 35 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months1

Buyers · sellers0 · 1

Who	Did	Shares	Traded
Leonard ReynoChief Medical Officer	sold	10,000at $2.22	16 Jan 2026filed 16 Jan 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders145+27 on the quarter

New · exited52 · 25

Reported value$541.6M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
MORGAN STANLEYreduced · filed 13 Aug 2026	8,867,338$41.4M	-205,062−2.3%
RA CAPITAL MANAGEMENT, L.P.unchanged · filed 14 Aug 2026	8,000,000$37.4M	00.0%
BlackRock, Inc.added · filed 7 Aug 2026	7,896,718$36.9M	+5,848,192+285.5%
Lynx1 Capital Management LPadded · filed 12 Aug 2026	7,326,691$34.2M	+327,789+4.7%
Squadron Capital Management LLCadded · filed 14 Aug 2026	7,200,000$33.6M	+4,950,000+220.0%
Bain Capital Life Sciences Investors, LLCunchanged · filed 14 Aug 2026	7,171,910$33.5M	00.0%
JPMORGAN CHASE & COnew · filed 12 Aug 2026	4,747,424$20.7M	+4,747,424
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	4,417,731$20.6M	+555,879+14.4%
CITADEL ADVISORS LLCadded · filed 14 Aug 2026	4,187,580$19.6M	+1,676,565+66.8%
GOLDMAN SACHS GROUP INCadded · filed 14 Aug 2026	3,530,991$16.5M	+1,143,613+47.9%