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The company

Caribou Biosciences, Inc.

CRBU · Nasdaq

Health CareBiotechnologyNot moving yetSynthetic Biology / TechBio

CRBU stood above a rising 150-day average in 12 of the last 52 weekly readings, and has been out of that trend for the last 23 weeks. It is 72.4% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 23
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $95K
Officials’ trades on record: 0
Institutions holding: 135 (+5)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 12 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months5

Buyers · sellers0 · 4

Who	Did	Shares	Traded
Timothy P. KellyChief Technology Officer	sold	6,228at $1.93	25 Feb 2026filed 27 Feb 2026
Barbara G. McClungChief Legal Officer	sold	6,938at $1.96	24 Feb 2026filed 24 Feb 2026
Timothy P. KellyChief Technology Officer	sold	3,147at $1.96	24 Feb 2026filed 24 Feb 2026
Ruhi Ahmad KhanChief Business Officer	sold	6,938at $1.96	24 Feb 2026filed 24 Feb 2026
Tina M. AlbertsonChief Medical Officer	sold	1,066at $1.96	24 Feb 2026filed 24 Feb 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders135+5 on the quarter

New · exited27 · 22

Reported value$81.6M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
BlackRock, Inc.added · filed 7 Aug 2026	7,815,843$13.8M	+5,672,758+264.7%
Pfizer Incunchanged · filed 13 Aug 2026	4,690,431$7.9M	00.0%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	4,208,568$7.4M	+441,340+11.7%
MACKENZIE FINANCIAL CORPadded · filed 13 Aug 2026	3,650,796$6.4M	+2,708,010+287.2%
RENAISSANCE TECHNOLOGIES LLCadded · filed 13 Aug 2026	2,773,545$4.9M	+183,048+7.1%
Kynam Capital Management, LPunchanged · filed 14 Aug 2026	2,503,302$4.4M	00.0%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 2026	2,374,894$4.2M	+1,356,935+133.3%
STATE STREET CORPadded · filed 7 Aug 2026	1,632,914$2.9M	+1,209,651+285.8%
BANK OF AMERICA CORPadded · filed 14 Aug 2026	1,410,958$2.5M	+113,791+8.8%
TWO SIGMA INVESTMENTS, LPreduced · filed 14 Aug 2026	1,046,279$1.8M	-713,655−40.6%