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The company

Definium Therapeutics, Inc. - Common Shares

DFTX · Nasdaq

Health CareBiotechnologyJust started movingNeurotech

DFTX stood above a rising 150-day average in 52 of the last 52 weekly readings, every one of them. It is 1.2% above that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

Statistics

Rotation
Just started moving
Weeks in an uptrend
52 in a row
Industry in uptrend
16% -15 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$13.4M
Officials’ trades on record
0
Institutions holding
346 (+110)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 52 of 52 weeks.

20 Apr – 19 Oct
17%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$5.8M$0Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0
Sale orders, 12 months17
Buyers · sellers0 · 5
WhoDidSharesTraded
Brandi RobertsChief Financial Officersold3,377at $36.5725 Sep 2026filed 29 Sep 2026
Mark SullivanChief Legal Officersold14,051at $36.5725 Sep 2026filed 29 Sep 2026
Matthew T. WileyChief Commercial Officersold3,097at $36.5725 Sep 2026filed 29 Sep 2026
Robert BarrowChief Executive Officersold31,550at $36.5725 Sep 2026filed 29 Sep 2026
Daniel KarlinChief Medical Officersold10,853at $36.5725 Sep 2026filed 29 Sep 2026
Robert BarrowChief Executive Officersold19,023at $37.943 Sep 2026filed 4 Sep 2026
Matthew T. WileyChief Commercial Officersold2,867at $45.0325 Jun 2026filed 26 Jun 2026
Robert BarrowChief Executive Officersold29,208at $45.0325 Jun 2026filed 26 Jun 2026
Brandi RobertsChief Financial Officersold3,013at $45.0325 Jun 2026filed 26 Jun 2026
Daniel KarlinChief Medical Officersold10,035at $45.0325 Jun 2026filed 26 Jun 2026
Mark SullivanChief Legal Officersold13,008at $45.0325 Jun 2026filed 26 Jun 2026
Robert BarrowChief Executive Officersold24,431at $18.4725 Mar 2026filed 26 Mar 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders346+110 on the quarter
New · exited143 · 33
Reported value$5.2B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
BlackRock, Inc.added · filed 7 Aug 202611,232,834$528.4M+2,752,604+32.5%
Avoro Capital Advisors LLCadded · filed 14 Aug 20267,188,888$338.2M+2,188,888+43.8%
Driehaus Capital Management LLCadded · filed 14 Aug 20266,845,276$322.0M+933,387+15.8%
Jupiter Topco LLCnew · filed 14 Aug 20265,615,645$264.0M+5,615,645
Capital World Investorsnew · filed 12 Aug 20265,367,723$252.5M+5,367,723
FMR LLCadded · filed 13 Aug 20264,752,921$223.6M+2,943,311+162.6%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 20263,644,813$171.5M+1,149,414+46.1%
STATE STREET CORPadded · filed 7 Aug 20263,065,390$144.2M+593,517+24.0%
Capital International Investorsnew · filed 12 Aug 20262,963,410$139.4M+2,963,410
Octagon Capital Advisors LPadded · filed 14 Aug 20262,950,000$138.8M+510,000+20.9%
31 Dec 2025 – 30 Jun 2026
19177334Dec 25Mar 26Jun 26

Everyone who traded it

Brandi Roberts Company insiderChief Financial Officer · last 25 Sep 20260 · 2
Daniel Karlin Company insiderChief Medical Officer · last 25 Sep 20260 · 26
Mark Sullivan Company insiderChief Legal Officer · last 25 Sep 20260 · 10
Matthew T. Wiley Company insiderChief Commercial Officer · last 25 Sep 20260 · 2
Robert Barrow Company insiderChief Executive Officer · last 25 Sep 20262 · 29
Andreas Krebs Company insiderDirector · last 18 Sep 20260 · 0
Carol A. Vallone Company insiderDirector · last 18 Sep 20260 · 0
David W. Gryska Company insiderDirector · last 11 Jun 20262 · 0
Roger Adsett Company insiderDirector · last 11 Jun 20260 · 0
Roger Crystal Company insiderDirector · last 11 Jun 20260 · 0
Suzanne Louise Bruhn Company insiderDirector · last 11 Jun 20260 · 0
Carrie Liao Company insiderChief Accounting Officer · last 25 Mar 20250 · 3

Same industry

MRNA ModernaLeading+154%
ENTX Entera BioLeading+49%
XNCR XencorLeading+32%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Return on capital employedFY 2025 · to 31 Dec 2025-44.5%
Debt to equityFY 2025 · to 31 Dec 20250.12×
Interest coverFY 2025 · to 31 Dec 2025-30.34×
Share count trendFY 2025 · to 19 Feb 20260.9%
Cash and equivalentsFY 2025 · to 31 Dec 2025$257.8M

Analyst forecasts

No analyst forecasts yet.