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The company

Edgewise Therapeutics, Inc.

EWTX · Nasdaq

Health CareBiotechnologyJust dropped out

EWTX stood above a rising 150-day average in 47 of the last 52 weekly readings, and has been out of that trend for the last 1 week. It is 0.2% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Just dropped out
Weeks in an uptrend: out for 1
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $199K
Insider sales, 12 months: $36.9M
Officials’ trades on record: 0
Institutions holding: 214 (+15)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 47 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months1

Sale orders, 12 months14

Buyers · sellers1 · 6

Who	Did	Shares	Traded
Joanne M. DonovanCMO	sold	2,919at $43.41	13 Aug 2026filed 14 Aug 2026
Kevin KochPresident and CEO	sold	8,782at $43.64	12 Aug 2026filed 14 Aug 2026
Kevin KochPresident and CEO	sold	8,276at $43.66	12 Aug 2026filed 14 Aug 2026
Kevin KochPresident and CEO	sold	913at $44.33	12 Aug 2026filed 14 Aug 2026
John R. MooreGeneral Counsel	sold	2,439at $43.81	12 Aug 2026filed 14 Aug 2026
John R. MooreGeneral Counsel	sold	59at $44.41	12 Aug 2026filed 14 Aug 2026
John R. MooreGeneral Counsel	sold	99at $44.50	12 Aug 2026filed 14 Aug 2026
John R. MooreGeneral Counsel	sold	2,419at $43.80	12 Aug 2026filed 14 Aug 2026
Joanne M. DonovanCMO	sold	2,839at $43.78	12 Aug 2026filed 14 Aug 2026
Joanne M. DonovanCMO	sold	2,779at $43.71	12 Aug 2026filed 14 Aug 2026
Joanne M. DonovanCMO	sold	104at $44.43	12 Aug 2026filed 14 Aug 2026
Joanne M. DonovanCMO	sold	800at $44.52	12 Aug 2026filed 14 Aug 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders214+15 on the quarter

New · exited43 · 28

Reported value$4.8B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
ORBIMED ADVISORS LLCunchanged · filed 14 Aug 2026	15,518,492$630.5M	00.0%
Paradigm Biocapital Advisors LPadded · filed 14 Aug 2026	10,215,455$415.1M	+2,850,417+38.7%
RA CAPITAL MANAGEMENT, L.P.reduced · filed 14 Aug 2026	8,392,730$341.0M	-2,035,707−19.5%
BlackRock, Inc.added · filed 7 Aug 2026	6,606,336$268.4M	+133,345+2.1%
Jupiter Topco LLCnew · filed 14 Aug 2026	6,075,331$246.9M	+6,075,331
FMR LLCadded · filed 13 Aug 2026	5,489,135$223.0M	+4,472,083+439.7%
NOVO HOLDINGS A/Sunchanged · filed 14 Aug 2026	5,350,000$217.4M	00.0%
Driehaus Capital Management LLCadded · filed 14 Aug 2026	4,728,623$192.1M	+250,681+5.6%
PERCEPTIVE ADVISORS LLCreduced · filed 14 Aug 2026	4,373,974$177.7M	-50,000−1.1%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	3,860,670$156.9M	+72,509+1.9%