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The company

Structure Therapeutics Inc. - American Depositary Shares

GPCR · Nasdaq

Health CareBiotechnologyNot moving yetGLP-1

GPCR stood above a rising 150-day average in 24 of the last 52 weekly readings, and has been out of that trend for the last 27 weeks. It is 52.4% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

Statistics

Rotation
Not moving yet
Weeks in an uptrend
out for 27
Industry in uptrend
15% -17 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$0
Officials’ trades on record
1
Institutions holding
185 (-3)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 24 of 52 weeks.

17 Apr – 16 Oct
16%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$1$0$1Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

1 disclosed lines: House 0, Senate 1, executive 0; 1 people.

WhoDidAmountTraded
Thomas R. Carper Senate: U.S. Senate eFDSenatorsoldspouse$1k–$15k4 Oct 2023filed 2 Nov 2023

Insiders

Buy orders, 12 months0
Sale orders, 12 months0
Buyers · sellers0 · 0
WhoDidSharesTraded
Crespo Blas CollCHIEF MEDICAL OFFICERsold4,008at $36.1521 Sep 2026filed 22 Sep 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold1,300at $45.861 Sep 2026filed 2 Sep 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold4,539at $47.201 Sep 2026filed 2 Sep 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold100at $47.831 Sep 2026filed 2 Sep 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold3,020at $53.1318 Aug 2026filed 19 Aug 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold519at $54.2018 Aug 2026filed 19 Aug 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold400at $55.0518 Aug 2026filed 19 Aug 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold3,100at $49.294 Aug 2026filed 5 Aug 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold839at $50.034 Aug 2026filed 5 Aug 2026
Fmr Llc10% owner, Othersold1,367at $50.0722 Jul 2026filed 24 Jul 2026
Fmr Llc10% owner, Othersold16,085at $50.0722 Jul 2026filed 24 Jul 2026
Xichen LinCHIEF SCIENTIFIC OFFICERsold6,278at $50.8014 Jul 2026filed 15 Jul 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders185-3 on the quarter
New · exited29 · 32
Reported value$3.6B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
FMR LLCreduced · filed 13 Aug 20267,810,306$419.2M-593,143−7.1%
WELLINGTON MANAGEMENT GROUP LLPadded · filed 14 Aug 20267,379,433$396.1M+119,146+1.6%
Avoro Capital Advisors LLCunchanged · filed 14 Aug 20266,555,555$351.8M00.0%
Jupiter Topco LLCnew · filed 14 Aug 20265,204,212$279.3M+5,204,212
Deep Track Capital, LPadded · filed 14 Aug 20264,740,072$254.4M+460,224+10.8%
BVF INCreduced · filed 14 Aug 20263,366,823$180.7M-92,535−2.7%
MORGAN STANLEYadded · filed 13 Aug 20262,806,640$150.6M+501,183+21.7%
ORBIMED ADVISORS LLCadded · filed 14 Aug 20262,209,400$118.6M+733,997+49.7%
PRINCIPAL FINANCIAL GROUP INCreduced · filed 4 Aug 20261,752,753$94.1M-1,011−0.1%
AMERICAN CENTURY COMPANIES INCadded · filed 12 Aug 20261,682,179$90.3M+244,148+17.0%
31 Mar 2023 – 30 Jun 2026
38110182Mar 23Dec 23Dec 24Sep 25Jun 26

News

No headline names it lately.

Everyone who traded it

Crespo Blas Coll Company insiderCHIEF MEDICAL OFFICER · last 21 Sep 20260 · 0
Xichen Lin Company insiderCHIEF SCIENTIFIC OFFICER · last 1 Sep 20260 · 0
John Joseph Berrios Company insiderChief Commercial Officer · last 6 Aug 20260 · 0
FMR LLC Company insider10% owner, Other · last 22 Jul 20260 · 0
Angus C. Russell Company insiderDirector · last 17 Jun 20260 · 0
Daniel G. Welch Company insiderDirector · last 17 Jun 20260 · 0
Eric Dobmeier Company insiderDirector · last 17 Jun 20260 · 0
Joanne Waldstreicher Company insiderDirector · last 17 Jun 20260 · 0
Sharon Tetlow Company insiderDirector · last 17 Jun 20260 · 0
Ted W. Love Company insiderDirector · last 17 Jun 20260 · 0
Matthew Lang Company insiderCOO & GC · last 15 Apr 20260 · 0
Ashley Hall Company insiderChief Development Officer · last 19 Mar 20260 · 0

Same industry

MRNA ModernaLeading+147%
ENTX Entera BioLeading+37%
XNCR XencorLeading+30%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Return on capital employedFY 2025 · to 31 Dec 2025-11.6%
Share count trendFY 2025 · to 15 Feb 20260.0%
Cash and equivalentsFY 2025 · to 31 Dec 2025$799.6M
Free cash flowFY 2025 · to 31 Dec 2025−$225.8M

Analyst forecasts

No analyst forecasts yet.