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The company

Lexicon Pharmaceuticals, Inc.

LXRX · Nasdaq

Health CareBiotechnologyNot moving yet

LXRX stood above a rising 150-day average in 44 of the last 52 weekly readings, and has been out of that trend for the last 4 weeks. It is 24.8% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 4
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $5.4M
Insider sales, 12 months: $0
Officials’ trades on record: 0
Institutions holding: 144 (+16)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 44 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months9

Sale orders, 12 months0

Buyers · sellers3 · 0

Who	Did	Shares	Traded
Raymond DebbaneDirector	bought	2,000at $1.49	25 Feb 2026filed 27 Feb 2026
Raymond DebbaneDirector	bought	100,000at $1.47	23 Feb 2026filed 25 Feb 2026
Raymond DebbaneDirector	bought	100,000at $1.48	20 Feb 2026filed 23 Feb 2026
Raymond DebbaneDirector	bought	50,000at $1.44	19 Feb 2026filed 23 Feb 2026
Raymond DebbaneDirector	bought	133,688at $1.32	18 Feb 2026filed 18 Feb 2026
Raymond DebbaneDirector	bought	76,857at $1.31	17 Feb 2026filed 18 Feb 2026
Raymond DebbaneDirector	bought	57,952at $1.31	13 Feb 2026filed 18 Feb 2026
Invus Global Management, LlcDirector, 10% owner	bought	1,538,462at $1.30	2 Feb 2026filed 4 Feb 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders144+16 on the quarter

New · exited44 · 29

Reported value$875.9M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Artal Group S.A.added · filed 13 Aug 2026	175,156,062$420.4M	+20,421,735+13.2%
FMR LLCadded · filed 13 Aug 2026	51,782,045$124.3M	+6,725,707+14.9%
Siren, L.L.C.unchanged · filed 13 Aug 2026	44,303,518$106.3M	00.0%
Sessa Capital IM, L.P.added · filed 14 Aug 2026	18,960,836$45.5M	+1,047,875+5.8%
BlackRock, Inc.added · filed 7 Aug 2026	17,348,741$41.6M	+14,026,522+422.2%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	9,901,208$23.8M	+382,041+4.0%
Point72 Asset Management, L.P.added · filed 14 Aug 2026	8,251,325$19.8M	+436,719+5.6%
GEODE CAPITAL MANAGEMENT, LLCadded · filed 12 Aug 2026	6,244,372$15.0M	+3,075,261+97.0%
STATE STREET CORPadded · filed 7 Aug 2026	4,917,769$11.8M	+3,953,731+410.1%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 2026	2,357,749$5.7M	+1,811,149+331.3%