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The company

Mirum Pharmaceuticals, Inc.

MIRM · Nasdaq

Health CareBiotechnologyNot moving yet

MIRM stood above a rising 150-day average in 41 of the last 52 weekly readings, and has been out of that trend for the last 11 weeks. It is 17.5% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 11
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $18.0M
Insider sales, 12 months: $72.8M
Officials’ trades on record: 0
Institutions holding: 302 (+14)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 41 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months1

Sale orders, 12 months42

Buyers · sellers1 · 7

Who	Did	Shares	Traded
Eric BjerkholtCHIEF FINANCIAL OFFICER	sold	9,943at $98.37	14 Sep 2026filed 15 Sep 2026
Jolanda HoweSVP, GLOBAL CONTROLLER	sold	658at $100.00	2 Sep 2026filed 3 Sep 2026
Christopher PeetzCHIEF EXECUTIVE OFFICER	sold	8,312at $98.08	1 Sep 2026filed 3 Sep 2026
Christopher PeetzCHIEF EXECUTIVE OFFICER	sold	21,688at $98.91	1 Sep 2026filed 3 Sep 2026
Jolanda HoweSVP, GLOBAL CONTROLLER	sold	40,000at $100.00	18 Aug 2026filed 19 Aug 2026
Eric BjerkholtCHIEF FINANCIAL OFFICER	sold	6,001at $99.90	11 Aug 2026filed 12 Aug 2026
Christopher PeetzCHIEF EXECUTIVE OFFICER	sold	11,683at $98.51	10 Aug 2026filed 11 Aug 2026
Christopher PeetzCHIEF EXECUTIVE OFFICER	sold	6,017at $99.25	10 Aug 2026filed 11 Aug 2026
Christopher PeetzCHIEF EXECUTIVE OFFICER	sold	2,300at $100.14	10 Aug 2026filed 11 Aug 2026
Jolanda HoweSVP, GLOBAL CONTROLLER	sold	1,840at $105.29	3 Aug 2026filed 5 Aug 2026
Eric BjerkholtCHIEF FINANCIAL OFFICER	sold	3,124at $121.67	6 Jul 2026filed 8 Jul 2026
Eric BjerkholtCHIEF FINANCIAL OFFICER	sold	1,048at $122.43	6 Jul 2026filed 8 Jul 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders302+14 on the quarter

New · exited57 · 38

Reported value$7.9B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Frazier Life Sciences Management, L.P.unchanged · filed 14 Aug 2026	7,679,684$899.1M	00.0%
Jupiter Topco LLCnew · filed 14 Aug 2026	5,909,184$691.7M	+5,909,184
BlackRock, Inc.added · filed 7 Aug 2026	4,459,741$514.0M	+310,220+7.5%
FMR LLCadded · filed 13 Aug 2026	3,670,314$429.7M	+1,704,939+86.7%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 2026	2,377,019$278.3M	+944,936+66.0%
STATE STREET CORPadded · filed 7 Aug 2026	2,305,461$254.2M	+227,801+11.0%
VANGUARD CAPITAL MANAGEMENT LLCreduced · filed 13 Aug 2026	2,254,109$263.9M	-160,667−6.7%
TWO SIGMA INVESTMENTS, LPadded · filed 14 Aug 2026	2,009,559$81.2M	+1,046,879+108.7%
UBS Group AGreduced · filed 13 Aug 2026	1,827,387$44.9M	-157,735−7.9%
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLCadded · filed 12 Aug 2026	1,404,741$164.5M	+1,069,072+318.5%