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The company

Milestone Pharmaceuticals Inc. - Common Shares

MIST · Nasdaq

Health CareBiotechnologyNot moving yet

MIST stood above a rising 150-day average in 14 of the last 52 weekly readings, and has been out of that trend for the last 38 weeks. It is 45.8% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 38
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $2.4M
Officials’ trades on record: 0
Institutions holding: 76 (-5)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 14 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months13

Buyers · sellers0 · 5

Who	Did	Shares	Traded
Joseph OlivetoPresident and CEO	sold	36,500at $2.26	16 Apr 2026filed 20 Apr 2026
Joseph OlivetoPresident and CEO	sold	34,523at $1.93	26 Jan 2026filed 28 Jan 2026
Lorenz MullerChief Commercial Officer	sold	11,180at $1.93	26 Jan 2026filed 28 Jan 2026
Amit HasijaCFO & EVP of Corp. Development	sold	12,245at $1.93	26 Jan 2026filed 28 Jan 2026
David BharuchaChief Medical Officer	sold	12,245at $1.93	26 Jan 2026filed 28 Jan 2026
Jeffrey Edward NelsonChief Operating Officer	sold	12,245at $1.93	26 Jan 2026filed 28 Jan 2026
Joseph OlivetoPresident and CEO	sold	43,000at $2.25	8 Jan 2026filed 9 Jan 2026
Joseph OlivetoPresident and CEO	sold	500at $2.25	7 Jan 2026filed 9 Jan 2026
Joseph OlivetoPresident and CEO	sold	133,054at $2.32	15 Dec 2025filed 28 Jan 2026
Lorenz MullerChief Commercial Officer	sold	53,566at $2.32	15 Dec 2025filed 28 Jan 2026
Amit HasijaCFO & EVP of Corp. Development	sold	58,007at $2.32	15 Dec 2025filed 28 Jan 2026
David BharuchaChief Medical Officer	sold	58,007at $2.32	15 Dec 2025filed 28 Jan 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders76-5 on the quarter

New · exited7 · 12

Reported value$66.3M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Pavaki Capital Management LLCadded · filed 7 Aug 2026	9,067,848$12.2M	+5,000+0.1%
RTW INVESTMENTS, LPadded · filed 14 Aug 2026	7,833,336$10.5M	+1,502,335+23.7%
Propel Bio Management, LLCadded · filed 13 Aug 2026	7,429,590$10.0M	+3,311,269+80.4%
Point72 Asset Management, L.P.added · filed 14 Aug 2026	5,411,138$7.3M	+4,325,455+398.4%
Simplify Asset Management Inc.added · filed 16 Jul 2026	3,349,379$4.5M	+1,842,974+122.3%
MILLENNIUM MANAGEMENT LLCadded · filed 14 Aug 2026	3,142,219$4.2M	+1,597,894+103.5%
TWO SIGMA INVESTMENTS, LPreduced · filed 14 Aug 2026	2,040,015$2.7M	-277,161−12.0%
MARSHALL WACE, LLPreduced · filed 13 Aug 2026	1,797,695$2.4M	-146,835−7.6%
Kalehua Capital Management LLCnew · filed 14 Aug 2026	1,269,237$1.7M	+1,269,237
Lion Point Capital, LPunchanged · filed 14 Aug 2026	820,000$1.1M	00.0%