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The company

Prime Medicine, Inc.

PRME · Nasdaq

Health CareBiotechnologyAbove a falling average

PRME stood above a rising 150-day average in 9 of the last 52 weekly readings, and has been out of that trend for the last 38 weeks. It is 17.0% above that average now. Biotechnology: 18% of its 561 stocks in an uptrend (−14 points in four weeks); Health Care: 28% (−9 points in four weeks).

SEC filings

Statistics

Rotation: Above a falling average
Weeks in an uptrend: out for 38
Industry in uptrend: 18% -14 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $0
Officials’ trades on record: 0
Institutions holding: 177 (-3)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 9 of 52 weeks.

21 Apr – 20 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months0

Buyers · sellers0 · 0

No open-market buy or sale by its insiders on record.

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders177-3 on the quarter

New · exited23 · 26

Reported value$372.1M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Alphabet Inc.unchanged · filed 7 Aug 2026	16,562,498$61.1M	00.0%
BlackRock, Inc.added · filed 7 Aug 2026	9,602,041$35.4M	+1,100,333+12.9%
ARK Investment Management LLCadded · filed 14 Aug 2026	8,348,746$30.8M	+2,101,919+33.6%
STATE STREET CORPadded · filed 7 Aug 2026	7,576,460$28.0M	+1,231,335+19.4%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	4,522,640$16.7M	+48,478+1.1%
Balyasny Asset Management L.P.reduced · filed 14 Aug 2026	3,969,082$14.6M	-154,283−3.7%
GOLDMAN SACHS GROUP INCadded · filed 14 Aug 2026	3,430,518$12.7M	+2,460,093+253.5%
Casdin Capital, LLCunchanged · filed 14 Aug 2026	3,167,175$11.7M	00.0%
Woodline Partners LPadded · filed 14 Aug 2026	3,003,904$11.1M	+5910.0%
UBS Group AGreduced · filed 13 Aug 2026	2,794,689$10.3M	-93,729−3.2%