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The company

Protagonist Therapeutics, Inc.

PTGX · Nasdaq

Health CareBiotechnologyIn trend

PTGX stood above a rising 150-day average in 52 of the last 52 weekly readings, every one of them. It is 4.6% above that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

Statistics

Rotation
In trend
Weeks in an uptrend
52 in a row
Industry in uptrend
15% -17 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$181.9M
Officials’ trades on record
2
Institutions holding
320 (+28)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 52 of 52 weeks.

17 Apr – 16 Oct
16%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$43.2M$0Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

2 disclosed lines: House 0, Senate 0, executive 2; 1 people.

WhoDidAmountTraded
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officesold$15k–$50k29 Jul 2026filed 22 Sep 2026
Donald J. Trump Executive branch: Office of Government EthicsWhite House Officesold$15k–$50k15 May 2026filed 1 Jul 2026

Insiders

Buy orders, 12 months0
Sale orders, 12 months32
Buyers · sellers0 · 7
WhoDidSharesTraded
Asif AliChief Financial Officersold12,595at $141.7730 Sep 2026filed 2 Oct 2026
Asif AliChief Financial Officersold46,034at $141.7830 Sep 2026filed 2 Oct 2026
Dinesh V. Ph D. PatelPresident and CEOsold7,278at $144.1010 Sep 2026filed 10 Sep 2026
Dinesh V. Ph D. PatelPresident and CEOsold63,548at $146.189 Sep 2026filed 10 Sep 2026
Dinesh V. Ph D. PatelPresident and CEOsold54,174at $145.878 Sep 2026filed 10 Sep 2026
Dinesh V. Ph D. PatelPresident and CEOsold34,239at $148.5211 Aug 2026filed 12 Aug 2026
Dinesh V. Ph D. PatelPresident and CEOsold65,761at $149.1110 Aug 2026filed 12 Aug 2026
William D. WaddillDirectorsold9,000at $117.9423 Jun 2026filed 25 Jun 2026
William D. WaddillDirectorsold9,000at $107.6810 Jun 2026filed 11 Jun 2026
William D. WaddillDirectorsold9,000at $99.6429 May 2026filed 1 Jun 2026
Dinesh V. Ph D. PatelPresident and CEOsold75,000at $100.1212 May 2026filed 12 May 2026
Dinesh V. Ph D. PatelPresident and CEOsold75,000at $100.1212 May 2026filed 14 May 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders320+28 on the quarter
New · exited68 · 40
Reported value$9.0B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
BlackRock, Inc.added · filed 7 Aug 202610,307,837$1.3B+528,468+5.4%
FARALLON CAPITAL MANAGEMENT, L.L.C.unchanged · filed 14 Aug 20266,348,906$778.2M00.0%
RTW INVESTMENTS, LPadded · filed 14 Aug 20265,061,175$620.4M+2,1220.0%
VANGUARD PORTFOLIO MANAGEMENT LLCnew · filed 13 Aug 20263,629,298$444.9M+3,629,298
WELLINGTON MANAGEMENT GROUP LLPreduced · filed 14 Aug 20263,416,781$418.8M-182,863−5.1%
UBS Group AGreduced · filed 13 Aug 20263,399,221$416.7M-1,778,575−34.4%
STATE STREET CORPadded · filed 7 Aug 20263,321,554$407.2M+204,805+6.6%
VANGUARD CAPITAL MANAGEMENT LLCnew · filed 13 Aug 20262,853,394$349.8M+2,853,394
JOHNSON & JOHNSONunchanged · filed 6 Aug 20262,449,183$300.2M00.0%
Invesco Ltd.added · filed 14 Aug 20262,340,667$286.9M+175,997+8.1%
31 Mar 2023 – 30 Jun 2026
114213312Mar 23Dec 23Dec 24Sep 25Jun 26

News

No headline names it lately.

Everyone who traded it

Asif Ali Company insiderChief Financial Officer · last 30 Sep 20260 · 12
Dinesh P.H. D. Patel V Company insiderPresident and CEO · last 10 Sep 20261 · 31
Donald J. Trump Executive branchWhite House Office · last 29 Jul 20260 · 2
William D. Waddill Company insiderDirector · last 23 Jun 20260 · 12
Bryan Giraudo Company insiderDirector · last 8 May 20262 · 2
Arturo Molina Company insiderChief Medical Officer · last 26 Mar 20260 · 14
Harold E. Selick Company insiderDirector · last 26 Mar 20261 · 1
Lewis T. Williams Company insiderDirector · last 17 Feb 20260 · 1
Sarah A. O'Dowd Company insiderDirector · last 2 Jan 20260 · 0
Suneel Gupta Company insiderChief Development Officer · last 26 Nov 20241 · 3
Daniel N. Swisher Jr. Company insiderDirector · last 26 Oct 20230 · 0
Sarah B. Noonberg Company insiderDirector · last 16 Jan 20230 · 2

Same industry

MRNA ModernaLeading+147%
ENTX Entera BioLeading+37%
XNCR XencorLeading+30%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Operating profit marginFY 2025 · to 31 Dec 2025-344%
Return on capital employedFY 2025 · to 31 Dec 2025-25.4%
Research spendFY 2025 · to 31 Dec 2025346%
Share count trendFY 2025 · to 18 Feb 20262.0%
Cash and equivalentsFY 2025 · to 31 Dec 2025$128.4M
Free cash flowFY 2025 · to 31 Dec 2025$56.1M

Analyst forecasts

No analyst forecasts yet.