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The company

Palvella Therapeutics, Inc.

PVLA · Nasdaq

Health CareBiotechnologyJust dropped out

PVLA stood above a rising 150-day average in 49 of the last 52 weekly readings, and has been out of that trend for the last 1 week. It is 7.7% below that average now. Biotechnology: 16% of its 561 stocks in an uptrend (−15 points in four weeks); Health Care: 26% (−10 points in four weeks).

SEC filings

Statistics

Rotation: Just dropped out
Weeks in an uptrend: out for 1
Industry in uptrend: 16% -15 in 4 wk
Insider buys, 12 months: $1.7M
Insider sales, 12 months: $22.2M
Officials’ trades on record: 0
Institutions holding: 191 (+17)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 49 of 52 weeks.

20 Apr – 19 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months3

Sale orders, 12 months18

Buyers · sellers2 · 3

Who	Did	Shares	Traded
George M. JenkinsDirector	sold	476at $121.14	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	2,072at $122.62	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	2,604at $123.29	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	920at $124.37	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	597at $125.33	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	505at $126.55	14 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	2,004at $128.52	13 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	1,644at $129.23	13 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	990at $130.48	13 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	1,035at $131.49	13 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	579at $132.40	13 Oct 2026filed 14 Oct 2026
George M. JenkinsDirector	sold	922at $133.72	13 Oct 2026filed 14 Oct 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders191+17 on the quarter

New · exited39 · 21

Reported value$2.0B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
MONTANOVA CAPITAL, LLCreduced · filed 14 Aug 2026	1,135,406$173.5M	-18,090−1.6%
JENNISON ASSOCIATES LLCadded · filed 3 Aug 2026	960,619$146.8M	+320,008+50.0%
BlackRock, Inc.added · filed 7 Aug 2026	918,357$140.3M	+231,504+33.7%
Frazier Life Sciences Management, L.P.unchanged · filed 14 Aug 2026	882,400$134.8M	00.0%
First Light Asset Management, LLCreduced · filed 14 Aug 2026	771,901$118.0M	-208,857−21.3%
BVF INCreduced · filed 14 Aug 2026	672,789$102.8M	-288,200−30.0%
STATE STREET CORPadded · filed 7 Aug 2026	653,172$99.8M	+194,173+42.3%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	513,794$78.5M	+36,500+7.6%
FRONTIER CAPITAL MANAGEMENT CO LLCadded · filed 14 Aug 2026	478,833$73.2M	+104,798+28.0%
FEDERATED HERMES, INC.unchanged · filed 12 Aug 2026	433,015$66.2M	00.0%