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The company

Q32 Bio Inc.

QTTB · Nasdaq

Health CareBiotechnologyNot moving yet

QTTB stood above a rising 150-day average in 46 of the last 52 weekly readings, and has been out of that trend for the last 5 weeks. It is 17.0% below that average now. Biotechnology: 18% of its 561 stocks in an uptrend (−9 points in four weeks); Health Care: 28% (−6 points in four weeks).

Statistics

Rotation
Not moving yet
Weeks in an uptrend
out for 5
Industry in uptrend
18% -9 in 4 wk
Insider buys, 12 months
$60.0M
Insider sales, 12 months
$856K
Officials’ trades on record
0
Institutions holding
68 (+17)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 46 of 52 weeks.

23 Apr – 22 Oct
18%29%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has been slipping.

Money in and out

1 Nov 2024 – 1 Oct 2026
$0$57.8MNov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months3
Sale orders, 12 months11
Buyers · sellers3 · 3
WhoDidSharesTraded
Lee KalowskiCFO and Presidentsold1,301at $8.326 Oct 2026filed 14 Oct 2026
Shelia M. VioletteChief Scientific Officersold917at $8.326 Oct 2026filed 14 Oct 2026
Jodie Pope MorrisonCEOsold3,221at $8.326 Oct 2026filed 14 Oct 2026
Shelia M. VioletteChief Scientific Officersold2,798at $16.5625 Aug 2026filed 27 Aug 2026
Jodie Pope MorrisonCEOsold9,845at $16.5625 Aug 2026filed 27 Aug 2026
Lee KalowskiCFO and Presidentsold3,972at $16.5625 Aug 2026filed 27 Aug 2026
Orbimed Advisors LlcDirector, 10% ownerbought1,250,000at $8.0028 May 2026filed 1 Jun 2026
Orbimed Advisors LlcDirector, 10% ownerbought625,000at $8.0028 May 2026filed 1 Jun 2026
Diyong XuDirector, 10% ownerbought1,250,000at $8.0028 May 2026filed 1 Jun 2026
Diyong XuDirector, 10% ownerbought625,000at $8.0028 May 2026filed 1 Jun 2026
Shelia M. VioletteChief Scientific Officersold2,815at $4.5125 Feb 2026filed 27 Feb 2026
Jodie Pope MorrisonCEOsold9,896at $4.5125 Feb 2026filed 27 Feb 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders68+17 on the quarter
New · exited27 · 9
Reported value$279.3M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
ORBIMED ADVISORS LLCadded · filed 14 Aug 20264,127,987$52.6M+1,875,000+83.2%
Boxer Capital Management, LLCnew · filed 14 Aug 20263,149,310$40.1M+3,149,310
Atlas Venture Life Science Advisors, LLCadded · filed 13 Aug 20262,717,106$34.6M+625,000+29.9%
BVF INCnew · filed 14 Aug 20262,350,000$29.9M+2,350,000
RA CAPITAL MANAGEMENT, L.P.new · filed 14 Aug 20262,332,457$29.7M+2,332,457
Point72 Asset Management, L.P.new · filed 14 Aug 20261,173,396$14.9M+1,173,396
Opaleye Management Inc.reduced · filed 14 Aug 2026931,000$11.9M-325,228−25.9%
Logos Global Management LPnew · filed 14 Aug 2026800,000$10.2M+800,000
SummitTX Capital, L.P.new · filed 14 Aug 2026733,774$9.3M+733,774
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026518,803$6.6M+212,402+69.3%
31 Mar 2024 – 30 Jun 2026
386286Mar 24Sep 24Jun 25Dec 25Jun 26

Everyone who traded it

Jodie Pope Morrison Company insiderCEO · last 6 Oct 20260 · 5
Lee Kalowski Company insiderCFO and President · last 6 Oct 20260 · 5
Shelia M. Violette Company insiderChief Scientific Officer · last 6 Oct 20260 · 4
Isaac Manke Company insiderDirector · last 30 Jun 20260 · 0
Arthur Tzianabos Company insiderDirector · last 12 Jun 20260 · 13
David S. Grayzel Company insiderDirector · last 12 Jun 20260 · 0
Diyong Xu Company insiderDirector, 10% owner · last 12 Jun 20261 · 0
Kathleen Laporte Company insiderDirector · last 12 Jun 20260 · 0
Mark T. Iwicki Company insiderDirector · last 12 Jun 20260 · 0
Mary Thistle Company insiderDirector · last 12 Jun 20260 · 0
Sven Ante Lundberg Company insiderDirector · last 12 Jun 20260 · 0
ORBIMED ADVISORS LLC Company insiderDirector, 10% owner · last 28 May 20261 · 0

Same industry

MRNA ModernaLeading+118%
ENTX Entera BioLeading+51%
XNCR XencorLeading+44%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Operating profit marginFY 2025 · to 31 Dec 202531.5%
Free cash flow marginFY 2025 · to 31 Dec 2025-62.4%
Return on capital employedFY 2025 · to 31 Dec 202533.5%
Cash conversionFY 2025 · to 31 Dec 2025-112%
Interest coverFY 2025 · to 31 Dec 202516.02×
Research spendFY 2025 · to 31 Dec 202535.6%
Share count trendFY 2025 · to 1 Mar 202613.8%
Cash and equivalentsFY 2025 · to 31 Dec 2025$48.3M
Free cash flowFY 2025 · to 31 Dec 2025−$33.5M

Analyst forecasts

No analyst forecasts yet.