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The company

Rhythm Pharmaceuticals, Inc.

RYTM · Nasdaq

Health CareBiotechnologyNot moving yet

RYTM stood above a rising 150-day average in 24 of the last 52 weekly readings, and has been out of that trend for the last 4 weeks. It is 11.0% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

Statistics

Rotation
Not moving yet
Weeks in an uptrend
out for 4
Industry in uptrend
15% -17 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$75.7M
Officials’ trades on record
1
Institutions holding
288 (+19)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 24 of 52 weeks.

17 Apr – 16 Oct
16%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$45.6M$0Nov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

1 disclosed lines: House 0, Senate 0, executive 1; 1 people.

WhoDidAmountTraded
Eric S. Lander Executive branch: Office of Government EthicsOffice of Science and Technology Policysold$50k–$100k10 Jun 2021filed 8 Sep 2021

Insiders

Buy orders, 12 months0
Sale orders, 12 months22
Buyers · sellers0 · 9
WhoDidSharesTraded
David P. MeekerPresident and CEOsold6,439at $101.7514 Sep 2026filed 14 Sep 2026
David P. MeekerPresident and CEOsold30,746at $102.3514 Sep 2026filed 14 Sep 2026
David P. MeekerPresident and CEOsold8,698at $103.4314 Sep 2026filed 14 Sep 2026
David P. MeekerPresident and CEOsold1,817at $104.5514 Sep 2026filed 14 Sep 2026
David P. MeekerPresident and CEOsold2,300at $105.1914 Sep 2026filed 14 Sep 2026
Hunter C. SmithChief Financial Officersold23,072at $104.5931 Aug 2026filed 1 Sep 2026
Hunter C. SmithChief Financial Officersold11,514at $105.3731 Aug 2026filed 1 Sep 2026
Hunter C. SmithChief Financial Officersold28,188at $106.2031 Aug 2026filed 1 Sep 2026
Jennifer Kayden LeeEVP, Head of North Americasold75,834at $117.3813 Aug 2026filed 14 Aug 2026
Alastair GarfieldChief Scientific Officersold2,007at $116.1113 Aug 2026filed 17 Aug 2026
Alastair GarfieldChief Scientific Officersold1,556at $117.0813 Aug 2026filed 17 Aug 2026
Alastair GarfieldChief Scientific Officersold3,400at $118.2813 Aug 2026filed 17 Aug 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders288+19 on the quarter
New · exited62 · 43
Reported value$8.3B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
RA CAPITAL MANAGEMENT, L.P.unchanged · filed 14 Aug 20266,666,837$740.2M00.0%
BlackRock, Inc.reduced · filed 7 Aug 20266,156,902$683.6M-80,249−1.3%
BAKER BROS. ADVISORS LPunchanged · filed 14 Aug 20265,604,483$622.3M00.0%
PRIMECAP MANAGEMENT COreduced · filed 14 Aug 20263,168,853$351.8M-248,656−7.3%
VANGUARD PORTFOLIO MANAGEMENT LLCadded · filed 13 Aug 20263,136,895$348.3M+96,177+3.2%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 20263,005,977$333.8M+38,152+1.3%
JPMORGAN CHASE & COnew · filed 12 Aug 20262,652,746$292.2M+2,652,746
PERCEPTIVE ADVISORS LLCadded · filed 14 Aug 20262,586,295$287.2M+212,500+9.0%
STATE STREET CORPadded · filed 7 Aug 20262,573,529$285.7M+301,678+13.3%
WESTFIELD CAPITAL MANAGEMENT CO LPadded · filed 12 Aug 20262,208,595$245.2M+279,472+14.5%
31 Mar 2023 – 30 Jun 2026
107194281Mar 23Dec 23Dec 24Sep 25Jun 26

News

No headline names it lately.

Everyone who traded it

David P. Meeker Company insiderPresident and CEO · last 14 Sep 20262 · 6
Hunter C. Smith Company insiderChief Financial Officer · last 31 Aug 20260 · 29
Manher Joshi Company insiderChief Medical Officer · last 17 Aug 20260 · 0
Alastair Garfield Company insiderChief Scientific Officer · last 13 Aug 20260 · 2
Jennifer Kayden Lee Company insiderEVP, Head of North America · last 13 Aug 20260 · 25
Joseph Shulman Company insiderChief Technical Officer · last 13 Aug 20260 · 31
Yann Mazabraud Company insiderEVP, Head of International · last 12 Aug 20260 · 11
Christophe Jean Company insiderDirector · last 24 Jun 20260 · 0
David W. J. McGirr Company insiderDirector · last 24 Jun 20260 · 1
Jennifer L. Good Company insiderDirector · last 24 Jun 20260 · 3
Lynn A. Tetrault Company insiderDirector · last 24 Jun 20260 · 5
Stuart A. Arbuckle Company insiderDirector · last 24 Jun 20260 · 0

Same industry

MRNA ModernaLeading+147%
ENTX Entera BioLeading+37%
XNCR XencorLeading+30%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Profit per saleFY 2025 · to 31 Dec 202589.7%
Operating profit marginFY 2025 · to 31 Dec 2025-101%
Free cash flow marginFY 2025 · to 31 Dec 2025-61.5%
Return on capital employedFY 2025 · to 31 Dec 2025-51.3%
Debt to equityFY 2025 · to 31 Dec 20250.78×
Research spendFY 2025 · to 31 Dec 202588.2%
Share count trendFY 2025 · to 24 Feb 20261.6%
Cash and equivalentsFY 2025 · to 31 Dec 2025$54.3M
Free cash flowFY 2025 · to 31 Dec 2025−$116.6M

Analyst forecasts

No analyst forecasts yet.