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The company

Silence Therapeutics Plc - American Depository Share

SLN · Nasdaq

Health CareBiotechnologyJust dropped out

SLN stood above a rising 150-day average in 34 of the last 52 weekly readings, and has been out of that trend for the last 1 week. It is 7.1% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Just dropped out
Weeks in an uptrend: out for 1
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $0
Officials’ trades on record: 0
Institutions holding: 67 (+16)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 34 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months0

Buyers · sellers0 · 0

Who	Did	Shares	Traded
Richard Ian Griffiths10% owner	sold	2,792,826	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	100,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	50,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	3,500	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	800,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	382,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	470,820	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	605,174	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	120,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	60,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	100,000	10 Aug 2026filed 13 Aug 2026
Richard Ian Griffiths10% owner	sold	865,112	6 Jul 2026filed 7 Jul 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders67+16 on the quarter

New · exited20 · 4

Reported value$237.8M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
Siren, L.L.C.added · filed 13 Aug 2026	3,311,438$36.4M	+400,000+13.7%
TCG Crossover Management, LLCunchanged · filed 14 Aug 2026	3,033,560$33.3M	00.0%
Redmile Group, LLCunchanged · filed 14 Aug 2026	2,164,777$23.8M	00.0%
Nantahala Capital Management, LLCreduced · filed 14 Aug 2026	1,346,731$14.8M	-800,000−37.3%
CITADEL ADVISORS LLCadded · filed 14 Aug 2026	1,329,625$14.6M	+94,818+7.7%
Nextech Invest Ltd.unchanged · filed 14 Aug 2026	952,400$10.5M	00.0%
MILLENNIUM MANAGEMENT LLCreduced · filed 14 Aug 2026	909,279$10.0M	-164,912−15.4%
Ikarian Capital, LLCreduced · filed 14 Aug 2026	830,784$1.8M	-35,000−4.0%
Tetragon Partners GP Ltdadded · filed 13 Aug 2026	764,256$8.4M	+134,095+21.3%
Soleus Capital Management, L.P.new · filed 11 Aug 2026	630,000$6.9M	+630,000