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The company

Tyra Biosciences, Inc.

TYRA · Nasdaq

Health CareBiotechnologyNot moving yet

TYRA stood above a rising 150-day average in 35 of the last 52 weekly readings, and has been out of that trend for the last 11 weeks. It is 31.1% below that average now. Biotechnology: 18% of its 561 stocks in an uptrend (−14 points in four weeks); Health Care: 28% (−9 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 11
Industry in uptrend: 18% -14 in 4 wk
Insider buys, 12 months: $40K
Insider sales, 12 months: $11.6M
Officials’ trades on record: 0
Institutions holding: 165 (+6)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 35 of 52 weeks.

21 Apr – 20 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months1

Sale orders, 12 months11

Buyers · sellers1 · 3

Who	Did	Shares	Traded
Ra Capital Management, L.p.Director, 10% owner	bought	9,078,529at $22.03	15 Sep 2026filed 17 Sep 2026
Rehan VerjeeDirector	bought	971.894at $20.58	9 Sep 2026filed 11 Sep 2026
Gilla KaplanDirector	sold	14,295at $36.97	25 Mar 2026filed 27 Mar 2026
Daniel BensenChief Discovery Officer	sold	2,128at $31.50	12 Feb 2026filed 13 Feb 2026
Daniel BensenChief Discovery Officer	sold	5,872at $33.37	12 Feb 2026filed 13 Feb 2026
Daniel BensenChief Discovery Officer	sold	6,983at $28.44	12 Jan 2026filed 20 Jan 2026
Daniel BensenChief Discovery Officer	sold	1,017at $29.08	12 Jan 2026filed 20 Jan 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders165+6 on the quarter

New · exited33 · 27

Reported value$2.1B

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
RA CAPITAL MANAGEMENT, L.P.unchanged · filed 14 Aug 2026	12,198,625$389.6M	00.0%
FMR LLCadded · filed 13 Aug 2026	8,920,513$284.9M	+1,172,865+15.1%
Jupiter Topco LLCnew · filed 14 Aug 2026	4,352,448$139.2M	+4,352,448
Alta Partners Management Company, L.P.unchanged · filed 22 Jul 2026	3,823,425$122.1M	00.0%
Nextech Invest Ltd.reduced · filed 14 Aug 2026	3,553,585$113.5M	-502,276−12.4%
TCG Crossover Management, LLCunchanged · filed 14 Aug 2026	3,248,980$103.8M	00.0%
BlackRock, Inc.added · filed 7 Aug 2026	3,031,972$96.8M	+814,043+36.7%
STATE STREET CORPadded · filed 7 Aug 2026	2,140,368$68.4M	+924,290+76.0%
Commodore Capital LPreduced · filed 14 Aug 2026	1,875,000$59.9M	-600,000−24.2%
Paradigm Biocapital Advisors LPreduced · filed 14 Aug 2026	1,828,607$58.4M	-226,384−11.0%