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Who

Darren S. Cline

Director

Company insider

Files Form 4 as: Director, Pliant Therapeutics; Director, Pyxis Oncology; Chief Commercial Officer, Xenon Pharmaceuticals; Director, Impel Pharmaceuticals; U.S. Chief Commercial Officer, Gw Pharmaceuticals; Director, Stemline Therapeutics; EVP, Commercial, Seattle Genetics Inc /wa.

In numbers

Trades disclosed
117
Buys
1
Sells
18
Bought
$94K
Sold
$5.5M
Companies
7
Companies where not an officer
4
First trade
13 Mar 2015
Last trade
11 Jun 2026
Last filed
12 Jun 2026

Companies traded

Where they are an officer
XENE Xenon PharmaceuticalsOfficer · Biotechnology · last 9 Jan 20260 buys · 0 sells
Gw PharmaceuticalsOfficer · last 5 May 20210 buys · 0 sells
Seattle Genetics Inc /waOfficer · last 29 Nov 20180 buys · 18 sells
Everywhere else they filed: board seats, 10% stakes, other companies
PLRX Pliant TherapeuticsDirector · Biotechnology · last 11 Jun 20260 buys · 0 sells
PYXS Pyxis OncologyDirector · Biotechnology · last 24 Mar 20261 buy · 0 sells
Impel PharmaceuticalsDirector · last 16 Jun 20230 buys · 0 sells
Stemline TherapeuticsDirector · last 10 Jun 20200 buys · 0 sells

Activity over time

1 Nov 2024 – 1 Oct 2026
101Nov 24May 25Nov 25Apr 26Oct 26

Buys above the line, sells below, each month.

Every trade

TradedCompanyWhatAmount
11 Jun 2026filed 12 Jun 2026PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—70,000 at $0.00filing
11 Jun 2026filed 12 Jun 2026PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—70,000 at $0.00filing
24 Mar 2026filed 25 Mar 2026PYXS Pyxis Oncologyoption or derivative · BiotechnologySEC FORM 4 Code A—45,867 at $0.00filing
24 Mar 2026filed 25 Mar 2026PYXS Pyxis Oncologyoption or derivative · BiotechnologySEC FORM 4 Code A—45,867 at $0.00filing
9 Jan 2026filed 9 Jan 2026XENE Xenon Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—40,000 at $0.00filing
9 Jan 2026filed 9 Jan 2026XENE Xenon Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—20,000 at $0.00filing
9 Jan 2026filed 9 Jan 2026XENE Xenon Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—40,000 at $0.00filing
9 Jan 2026filed 9 Jan 2026XENE Xenon Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—20,000 at $0.00filing
23 Jun 2025filed 24 Jun 2025XENE Xenon Pharmaceuticalsoption or derivative · BiotechnologySEC FORM 4 Code A—185,800 at $0.00filing
5 Jun 2025filed 9 Jun 2025PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—30,000 at $0.00filing
31 Mar 2025filed 2 Apr 2025PYXS Pyxis Oncologyoption or derivative · BiotechnologySEC FORM 4 Code A$36K36,979 at $0.98filing
13 Jun 2024filed 17 Jun 2024PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—26,764 at $0.00filing
26 Mar 2024filed 28 Mar 2024PYXS Pyxis OncologyBiotechnologySEC FORM 4 Code A—35,219 at $0.00filing
16 Jun 2023filed 20 Jun 2023Impel Pharmaceuticalsoption or derivativeSEC FORM 4 Code A—13,222 at $0.00filing
7 Jun 2023filed 8 Jun 2023PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—14,000 at $0.00filing
12 Apr 2023filed 14 Apr 2023Impel Pharmaceuticalsoption or derivativeSEC FORM 4 Code A—20,013 at $0.00filing
24 Mar 2023filed 28 Mar 2023PYXS Pyxis OncologyBiotechnologySEC FORM 4 Code A—139,355 at $0.00filing
6 Mar 2023filed 8 Mar 2023PLRX Pliant Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—22,000 at $0.00filing
31 Mar 2022filed 4 Apr 2022PYXS Pyxis OncologyBiotechnologySEC FORM 4 Code A—66,831 at $0.00filing
8 Dec 2021filed 9 Dec 2021PYXS Pyxis OncologyBiotechnologySEC FORM 4 Bought$94K10,000 at $9.39filing

News

Critical Analysis: Pyxis Oncology (NASDAQ:PYXS) versus Inovio Pharmaceuticals (NASDAQ:INO)PYXS · themarketsdaily.com · 8 Oct 2026

0 headlines in the last 90 days name Darren S. Cline; 1 article from the last 14 days about the 1 company they traded most, at most three about any one of them.

Sectors

Health Care1
Not placed18

Buys in green, sells in red, by the company’s sector.

Related people

Thomas Patrick KellyChief Financial Officer · Chief Financial Officer at Xenon Pharmaceuticals, filing Form 4 there in the last year
Ian MortimerPresident & CEO · President & CEO at Xenon Pharmaceuticals, filing Form 4 there in the last year
Dawn SvoronosDirector · Director at Xenon Pharmaceuticals, filing Form 4 there in the last year
Christopher John KenneyChief Medical Officer · Chief Medical Officer at Xenon Pharmaceuticals, filing Form 4 there in the last year
Steven GannonDirector · Director at Xenon Pharmaceuticals, filing Form 4 there in the last year
GordonMD Global Investments LP10% owner · Also traded PYXS in the last 90 days