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The company

Pyxis Oncology, Inc.

PYXS · Nasdaq

Health CareBiotechnologyNot moving yet

PYXS stood above a rising 150-day average in 15 of the last 52 weekly readings, and has been out of that trend for the last 3 weeks. It is 28.7% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

Statistics

Rotation
Not moving yet
Weeks in an uptrend
out for 3
Industry in uptrend
15% -17 in 4 wk
Insider buys, 12 months
$0
Insider sales, 12 months
$214K
Officials’ trades on record
0
Institutions holding
75 (+2)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 15 of 52 weeks.

17 Apr – 16 Oct
16%28%39%Apr 26Jun 26Jul 26Sep 26Oct 26

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026
−$200K$0$160KNov 24May 25Nov 25Apr 26Oct 26

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months1
Sale orders, 12 months1
Buyers · sellers1 · 1
WhoDidSharesTraded
Gordonmd Global Investments Lp10% ownerbought5,517,0001 Oct 2026filed 2 Oct 2026
Gordonmd Global Investments Lp10% ownerbought7,546,7661 Oct 2026filed 2 Oct 2026
Gordonmd Global Investments Lp10% ownerbought7,172,0001 Oct 2026filed 9 Oct 2026
Jakob DupontDirectorsold35,000at $3.0630 Jun 2026filed 2 Jul 2026
Rachel HumphreyDirectorsold13,896at $1.0321 Apr 2025filed 25 Mar 2026
Rachel HumphreyDirectorsold200at $0.9717 Apr 2025filed 25 Mar 2026
Rachel HumphreyDirectorsold1,400at $0.972714 Apr 2025filed 25 Mar 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders75+2 on the quarter
New · exited12 · 11
Reported value$100.7M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

ManagerSharesChange
GordonMD Global Investments LPadded · filed 14 Aug 202610,024,909$30.2M+5,903,039+143.2%
Pfizer Incunchanged · filed 13 Aug 20267,032,770$19.5M00.0%
Laurion Capital Management LPreduced · filed 13 Aug 20264,900,888$14.8M-96,445−1.9%
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 20262,075,997$6.2M+42,487+2.1%
Atle Fund Management ABadded · filed 24 Jul 2026966,459$2.9M+769,423+390.5%
BlackRock, Inc.added · filed 7 Aug 2026867,934$2.6M+79,095+10.0%
Palo Alto Investors LPreduced · filed 17 Aug 2026864,277$2.6M-146,233−14.5%
MARSHALL WACE, LLPadded · filed 13 Aug 2026830,544$2.5M+476,127+134.3%
RENAISSANCE TECHNOLOGIES LLCreduced · filed 13 Aug 2026772,232$2.3M-116,448−13.1%
GEODE CAPITAL MANAGEMENT, LLCreduced · filed 12 Aug 2026591,849$1.8M-6,272−1.0%
31 Mar 2023 – 30 Jun 2026
406488Mar 23Dec 23Dec 24Sep 25Jun 26

Everyone who traded it

GordonMD Global Investments LP Company insider10% owner · last 1 Oct 20261 · 0
Thomas Civik Company insiderCEO & Chairman of the Board · last 4 Sep 20261 · 0
Jakob Dupont Company insiderDirector · last 20 Aug 20260 · 1
Darren S. Cline Company insiderDirector · last 24 Mar 20261 · 0
Freda C. Lewis-Hall Company insiderDirector · last 24 Mar 20260 · 0
Jitendra Wadhane Company insiderPrin Fin & Acct Officer · last 24 Mar 20263 · 0
John L. Flavin Company insiderDirector · last 24 Mar 20260 · 0
Michael A. Metzger Company insiderDirector · last 24 Mar 20260 · 0
Rachel Humphrey Company insiderDirector · last 24 Mar 20260 · 3
Santhosh Palani Company insiderDirector · last 24 Mar 20260 · 0
Lara Sullivan Company insiderPresident, CEO & CMO · last 31 Mar 20250 · 5
Pamela Ann Connealy Company insiderCFO & COO · last 31 Mar 20255 · 0

Same industry

MRNA ModernaLeading+147%
ENTX Entera BioLeading+37%
XNCR XencorLeading+30%

Distance from each stock’s own 150-day average.

Government contracts

No federal award is tied to it.

From its SEC filings

Profit per saleFY 2025 · to 31 Dec 202582.8%
Operating profit marginFY 2025 · to 31 Dec 2025-609%
Free cash flow marginFY 2025 · to 31 Dec 2025-458%
Return on capital employedFY 2025 · to 31 Dec 2025-120%
Share count trendFY 2025 · to 20 Mar 20260.2%
Cash and equivalentsFY 2025 · to 31 Dec 2025$15.4M
Free cash flowFY 2025 · to 31 Dec 2025−$63.5M

Analyst forecasts

No analyst forecasts yet.