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The company

OnKure Therapeutics, Inc.

OKUR · Nasdaq

Health CareBiotechnologyNot moving yet

OKUR stood above a rising 150-day average in 32 of the last 52 weekly readings, and has been out of that trend for the last 8 weeks. It is 46.2% below that average now. Biotechnology: 15% of its 561 stocks in an uptrend (−17 points in four weeks); Health Care: 25% (−11 points in four weeks).

SEC filings

Statistics

Rotation: Not moving yet
Weeks in an uptrend: out for 8
Industry in uptrend: 15% -17 in 4 wk
Insider buys, 12 months: $0
Insider sales, 12 months: $10K
Officials’ trades on record: 0
Institutions holding: 74 (+27)

In the rotation

Each square a week: lit when it closed above a rising 150-day average. 32 of 52 weeks.

17 Apr – 16 Oct

Biotechnology: Few of its stocks are in an uptrend and the share has fallen sharply over four weeks. Health Care: A minority of its stocks are in an uptrend and the share has fallen sharply over four weeks.

Money in and out

1 Nov 2024 – 1 Oct 2026

Open-market buys above the line and sales below, in dollars.

Congress and officials

No member of Congress or official has disclosed a trade in it.

Insiders

Buy orders, 12 months0

Sale orders, 12 months8

Buyers · sellers0 · 2

Who	Did	Shares	Traded
Nicholas A. SaccomanoPresident and CEO	sold	87at $2.97	21 Sep 2026filed 23 Sep 2026
Jason A. LeveroneChief Financial Officer	sold	302at $2.97	21 Sep 2026filed 23 Sep 2026
Nicholas A. SaccomanoPresident and CEO	sold	86at $4.40	22 Jun 2026filed 24 Jun 2026
Jason A. LeveroneChief Financial Officer	sold	303at $4.40	22 Jun 2026filed 24 Jun 2026
Nicholas A. SaccomanoPresident and CEO	sold	86at $4.16	23 Mar 2026filed 24 Mar 2026
Jason A. LeveroneChief Financial Officer	sold	301at $4.16	23 Mar 2026filed 24 Mar 2026

Lines filed since 2 January 2026, newest first; every insider’s older lines are on their own page.

Institutions

Holders74+27 on the quarter

New · exited32 · 5

Reported value$159.1M

Quarter to 30 Jun 2026, against 31 Mar 2026; newest filing 31 Aug 2026.

Manager	Shares	Change
RA CAPITAL MANAGEMENT, L.P.unchanged · filed 14 Aug 2026	3,998,333$18.2M	00.0%
BVF INCadded · filed 14 Aug 2026	3,235,778$14.8M	+1,256,806+63.5%
ACORN CAPITAL ADVISORS, LLCunchanged · filed 14 Aug 2026	2,839,674$12.9M	00.0%
StepStone Group LPunchanged · filed 13 Aug 2026	2,660,612$12.1M	00.0%
ADAR1 Capital Management, LLCreduced · filed 14 Aug 2026	2,238,684$10.2M	-196,257−8.1%
Vivo Capital, LLCunchanged · filed 14 Aug 2026	1,927,710$8.8M	00.0%
Vestal Point Capital, LPreduced · filed 14 Aug 2026	1,825,699$8.3M	-14,120−0.8%
BlackRock, Inc.added · filed 7 Aug 2026	1,499,845$6.8M	+1,450,258+2924.7%
Trails Edge Capital Partners, LPnew · filed 14 Aug 2026	1,438,456$6.6M	+1,438,456
VANGUARD CAPITAL MANAGEMENT LLCadded · filed 13 Aug 2026	1,437,039$6.6M	+854,562+146.7%