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Who

Edward T. Mathers

Director

Company insider

Files Form 4 as: Director, OnKure Therapeutics; Director and 10% owner, MBX Biosciences; Director, Trevi Therapeutics; Director, Rhythm Pharmaceuticals; 10% owner, Korro Bio; 10% owner, SpyGlass Pharma; Director and 10% owner, NeueHealth; Director, Senti Biosciences Holdings.

In numbers

Trades disclosed
168
Buys
6
Sells
2
Bought
$64.6M
Sold
$1.3M
Companies
17
Companies where not an officer
16
First trade
3 Feb 2006
Last trade
7 Aug 2026
Last filed
11 Aug 2026

Companies traded

Where they are an officer
Medimmune Inc /deOfficer · last 18 Jun 20070 buys · 1 sell
Everywhere else they filed: board seats, 10% stakes, other companies
OKUR OnKure TherapeuticsDirector · Biotechnology · last 7 Aug 20260 buys · 0 sells
MBX MBX BiosciencesDirector, 10% owner · Biotechnology · last 4 Jun 20261 buy · 0 sells
TRVI Trevi TherapeuticsDirector · Biotechnology · last 3 Jun 20260 buys · 0 sells
RYTM Rhythm PharmaceuticalsDirector · Biotechnology · last 12 Mar 20260 buys · 0 sells
KRRO Korro Bio10% owner · Biotechnology · last 10 Mar 20262 buys · 0 sells
SGP SpyGlass Pharma10% owner · Medical Devices · last 9 Feb 20261 buy · 0 sells
NeueHealthDirector, 10% owner · last 2 Oct 20250 buys · 1 sell
SNTI Senti Biosciences HoldingsDirector · Biotechnology · last 25 Jun 20250 buys · 0 sells
Inozyme PharmaDirector · last 18 Jun 20240 buys · 0 sells
SVRA Savara10% owner · Biotechnology · last 17 Jul 20231 buy · 0 sells
SynlogicDirector · Biotechnology · last 22 Jun 20230 buys · 0 sells
AkouosDirector · last 1 Dec 20220 buys · 0 sells

Activity over time

1 Nov 2024 – 1 Oct 2026
101Nov 24May 25Nov 25Apr 26Oct 26

Buys above the line, sells below, each month.

Every trade

TradedCompanyWhatAmount
7 Aug 2026filed 11 Aug 2026OKUR OnKure Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—22,350 at $0.00filing
7 Aug 2026filed 11 Aug 2026OKUR OnKure Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—22,350 at $0.00filing
4 Jun 2026filed 8 Jun 2026OKUR OnKure Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—7,650 at $0.00filing
4 Jun 2026filed 8 Jun 2026OKUR OnKure Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—7,650 at $0.00filing
4 Jun 2026filed 5 Jun 2026MBX MBX Biosciencesoption or derivative · BiotechnologySEC FORM 4 Code A—12,500 at $0.00filing
4 Jun 2026filed 5 Jun 2026MBX MBX Biosciencesoption or derivative · BiotechnologySEC FORM 4 Code A—12,500 at $0.00filing
3 Jun 2026filed 4 Jun 2026TRVI Trevi Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—35,000 at $0.00filing
3 Jun 2026filed 4 Jun 2026TRVI Trevi Therapeuticsoption or derivative · BiotechnologySEC FORM 4 Code A—35,000 at $0.00filing
12 Mar 2026filed 16 Mar 2026RYTM Rhythm PharmaceuticalsBiotechnologySEC FORM 4 Code J—4,199 at $0.00filing
12 Mar 2026filed 16 Mar 2026RYTM Rhythm PharmaceuticalsBiotechnologySEC FORM 4 Code J—4,199 at $0.00filing
10 Mar 2026filed 12 Mar 2026KRRO Korro BioBiotechnologySEC FORM 4 Bought$2.3M207,100 at $11.11filing
10 Mar 2026filed 12 Mar 2026KRRO Korro Biooption or derivative · BiotechnologySEC FORM 4 Code P$2.7M242,945 at $11.11filing
10 Mar 2026filed 12 Mar 2026KRRO Korro Biooption or derivative · BiotechnologySEC FORM 4 Code P$2.7M242,945 at $11.11filing
10 Mar 2026filed 12 Mar 2026KRRO Korro BioBiotechnologySEC FORM 4 Bought$2.3M207,100 at $11.11filing
2 Mar 2026filed 4 Mar 2026RYTM Rhythm PharmaceuticalsBiotechnologySEC FORM 4 Code J—4,198 at $0.00filing
2 Mar 2026filed 4 Mar 2026RYTM Rhythm PharmaceuticalsBiotechnologySEC FORM 4 Code J—4,198 at $0.00filing
9 Feb 2026filed 11 Feb 2026SGP SpyGlass PharmaMedical DevicesSEC FORM 4 Code C—1,619,240filing
9 Feb 2026filed 11 Feb 2026SGP SpyGlass PharmaMedical DevicesSEC FORM 4 Code C—1,370,168filing
9 Feb 2026filed 11 Feb 2026SGP SpyGlass PharmaMedical DevicesSEC FORM 4 Code C—1,370,168filing
9 Feb 2026filed 11 Feb 2026SGP SpyGlass Pharmaoption or derivative · Medical DevicesSEC FORM 4 Code C—1,619,240filing

Sectors

Health Care6
Not placed2

Buys in green, sells in red, by the company’s sector.

Related people

Matthew BowenPrincipal Accounting Officer · Also traded GLUE in the last 90 days
Jean Francois FormelaDirector · Also traded KRRO in the last 90 days
Oliver DolanSenior Vice President, Finance · Also traded KRRO in the last 90 days
Lynx1 Capital Management LP10% owner · Also traded KRRO in the last 90 days
Ram AiyarPresident and CEO · Also traded KRRO in the last 90 days
Salomon AzoulayChief Medical Officer · Also traded MBX in the last 90 days